Chester County Medicine Winter 2020 - 15

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In summary we feel that the REDUCE-IT trial is a landmark
trial and will result in change in how we treat heart disease.
References:
1. Bhatt, Deepak L., et al. "Cardiovascular Risk Reduction with Icosapent Ethyl for
Hypertriglyceridemia: NEJM." New England Journal of Medicine, 3 Jan. 2019,
www.nejm.org/doi/full/10.1056/NEJMoa1812792.
2. "Can Triglycerides Affect My Heart Health?" Mayo Clinic, Mayo Foundation
for Medical Education and Research, 13 Sept. 2018, www.mayoclinic.org/diseasesconditions/high-blood-cholesterol/in-depth/triglycerides/art-20048186.
3. Commissioner, Office of the. "FDA Approves Use of Drug to Reduce Risk of
Cardiovascular Events in Certain Adult Patient Groups." U.S. Food and Drug
Administration, FDA, 2019, www.fda.gov/news-events/press-announcements/fdaapproves-use-drug-reduce-risk-cardiovascular-events-certain-adult-patient-groups.
4. "Hypertriglyceridemia Management According to the 2018 AHA/ACC Guideline."
American College of Cardiology, 2019, www.acc.org/latest-in-cardiology/
articles/2019/01/11/07/39/hypertriglyceridemia-management-according-to-the-2018aha-acc-guideline.
5. Kelley-Hedgepeth, Alyson. "The Complicated Relationship between Fish Oil and
Heart Health." Harvard Health Blog, 12 Dec. 2019, www.health.harvard.edu/blog/
the-complicated-relationship-between-fish-oil-and-heart-health-2019120418399.
6. Rubins, Hanna Bloomfield, et al. "Gemfibrozil for the Secondary Prevention
of Coronary Heart Disease in Men with Low Levels of High-Density Lipoprotein
Cholesterol: NEJM." New England Journal of Medicine, 31 Jan. 2020, www.
nejm.org/doi/10.1056/NEJM199908053410604?url_ver=Z39.88-2003&rfr_

id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dwww.ncbi.nlm.nih.gov.
7. Yokoyama, Mitsuhiro, et al. "Effects of Eicosapentaenoic Acid on Major Coronary
Events in Hypercholesterolaemic Patients (JELIS): a Randomised Open-Label, Blinded
Endpoint Analysis." Lancet (London, England), U.S. National Library of Medicine,
31 Mar. 2007, www.ncbi.nlm.nih.gov/pubmed/17398308.
8. Yuan, George, et al. "Hypertriglyceridemia: Its Etiology, Effects and Treatment."
CMAJ : Canadian Medical Association Journal = Journal De L'Association
Medicale Canadienne, Canadian Medical Association, 10 Apr. 2007,
www.ncbi.nlm.nih.gov/pmc/articles/PMC1839776/.

This article was written
in collaboration between
Mian Jan, M.D., Chairman,
Department of Medicine
Penn Medicine Chester
County Hospital, and Asad
Ali a medical student at Nova
Southeastern University
Florida rotating during a
rotation in medicine with
West Chester Cardiology.

CONSIDER MEMBERSHIP
in The Chester County Medical Society

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Established in 1828, the Chester County
Medical Society, founded by Dr. William
Darlington, M.D., is thought to be the oldest
county medical society in the State. The
Medical Society is involved in all aspects of
healthcare policy, practice, and education and
serves to advance the health of the community
and to protect and expand the healthcare
resources available to its citizens.
T he Chester County Medical Society works
collaboratively with the Pennsylvania
Medical Society, but our focus is on our local
community. The Society's role in Chester
County is to support, protect, and advocate
for our physicians and our patients. We look
forward to growing an important healthcare
service for our community that will benefit us
all, and we look forward to hearing from you.

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Legislative Dinner - "aka The Clam Bake" - an annual dinner for members to meet local
legislators in an informal setting - stay tuned for more details about the 2020 Clam Bake
in our Summer edition.
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Chester County Medicine Winter 2020

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