Lancaster Physician Winter 2020 - 30

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From the above data, the NIH concludes
that HRT cannot be recommended at any age
to reduce the risk of Alzheimer's Disease. This
is ample data to stimulate additional research
regarding menopause and dementia.
Are there any interventions which may
forestall or prevent Alzheimer's disease? The
Alzheimer's Foundation notes some dietary
supplements may be beneficial. Curcumin,
found in green tea, has been shown in a mouse
and beagle dog model to reduce the deposition
of amyloid protein in the brain: a pathologic
marker of Alzheimer's disease. DHA (docosahexaenoic acid) is the most abundant fatty acid
in the brain and supplementation prior to the
advent of cognitive decline may be beneficial.
Yoga, walking and weight training are
physical activities thought to be beneficial
in the treatment of Alzheimer's, particularly
when cognitive decline is mild. Deep breathing, an essential feature of yoga improves
oxygenation, which benefits neuronal

physiology. Exercise induces the expression
of antioxidant enzymes, which remove toxic
free radicals.

Medications may delay the progression of
dementia in Alzheimer's disease; these drugs are
acetylcholinesterase inhibitors such as Aricept.

There are some foods that have been
recommended by the Alzheimer's foundation: curry, green tea, and the MIND
(Mediterranean-DASH diet Intervention for
Neurodegenerative Delay) diet:

In summary, there is ample evidence that
menopause is a risk factor for Alzheimer's
disease, and estrogen decline likely plays a
role in the onset of the disease. While this
suggests that hormone replacement therapy
would be beneficial, evidence to support this
is currently lacking.

A SALAD, AT LEAST ONE VEGETABLE,
AND THREE SERVINGS OF WHOLE
GRAIN EVERY DAY.
BEANS EVERY OTHER DAY
POULTRY AND BERRIES TWICE A WEEK

SOURCES:
Mosconi L, Rahman A, Diaz I, Wu X, Scheyer O, Hristov
HW, et al. (2018) Increased Alzheimer's risk during
the menopause transition: A 3-year longitudinal brain
imaging study. PLoS ONE 13(12): e0207885. https://doi.
org/10.1371/journal.pone.0207885
https://ad.foundation/prevention

FISH ONCE A WEEK
Mental activities such as crossword puzzles,
adequate sleep, and meditation are also recommended to forestall cognitive impairment.

Guidelines for Women's Health Care: a resource manual,
fourth edition. The American College of Obstetrics and
(American College of Obstetrics and Gynecology, 2014)

Penn Medicine Lancaster General Health is proud to
welcome neurologist J. Gabriel Hou, MD, PhD, FAAN,
to our community.
Dr. Hou has extensive training and research in movement disorders,
including:
* Tic disorders
* Parkinson's disease
* Dystonia
* Restless leg syndrome
* Tremors
* Chorea
He provides advanced treatments including botulinum toxin
injections, deep brain stimulation and enteric levodopa pump therapy.
Medical School: China Medical University (Taiwan)
Doctoral Degree: Mount Sinai School of Medicine
Residency: Montefiore Medical Center, Albert Einstein College
of Medicine
Fellowship: Baylor College of Medicine
Board Certified: Neurology
Dr. Hou practices at the Lancaster General Health Neuroscience
Institute. For more information about the Institute, visit
LGHealth.org/Neuro
Neurology
Neuroscience Institute
2150 Harrisburg Pike, Suite 200 | Lancaster | 717-544-3170

Neuroscience_J.GabrielHou_LancPhysAD_7.375x4.833_2019.indd 1

12/3/19 11:36 AM

LANCASTER

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PHYSICIAN
https://doi https://www.ad.foundation/prevention http://www.LGHealth.org/Neuro
Lancaster Physician Winter 2020

Table of Contents for the Digital Edition of Lancaster Physician Winter 2020
