PCOC - Spring 2020 - 24

FEATURE

New CRISPR-based Technology
Developed to Control Pests with
Precision-Guided Genetics
CRISPR-based method sterilizes male insects for
population suppression of agricultural pests and
disease-carrying mosquitoes
By Mario Aguilera, Division of Biological Sciences, UC San Diego

C

Nikolay Kandul (left) and Omar Akbari at the Akbari laboratory in the new Tata
Hall for the Sciences.

24 

THE VOICE | WWW.PCOC.ORG

Combining historical lessons with modern genetic technologies, scientists at the University of California San
Diego have developed a new way to control and suppress
populations of insects, potentially including those that
ravage agricultural crops and transmit deadly diseases.
Using the CRISPR gene editing tool, Nikolay Kandul,
Omar Akbari and their colleagues at UC San Diego and
UC Berkeley devised a method of altering key genes
that control insect sex determination and fertility.
A description of the new "precision-guided sterile
insect technique," or pgSIT, was published Jan. 8 in
the journal Nature Communications.
When pgSIT-derived eggs are introduced into targeted populations, the researchers report, only adult
sterile males emerge, resulting in a novel, environmentally friendly and relatively low-cost method of
controlling pest populations in the future.
"CRISPR technology has empowered our team to
innovate a new, effective, species-specific, self-limiting,
safe and scalable genetic population control technology with remarkable potential to be developed and
utilized in a plethora of insect pests and disease vectors," said Akbari, an assistant professor in UC San
Diego's Division of Biological Sciences. "In the future,
we strongly believe this technology will be safely used
in the field to suppress and even eradicate target species locally, thereby revolutionizing how insects are
managed and controlled going forward."


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PCOC - Spring 2020

Table of Contents for the Digital Edition of PCOC - Spring 2020

President’s Message
EVP Message
The Benefits of Being a PCOC Member
Details About the Future of Pest Control Expo
Surviving a Technology Conversion: 10 Tech Upgrade Tips for Smooth Sailing
Pesticide Research Must Stay Transparent and Independent
New Technology to Control Pests with Precision-Guided Genetics
NPMA Federal Update
Insurance
State Capitol Report
Marketing
Firm Profile
Index to Advertisers
PCOC - Spring 2020 - Intro
PCOC - Spring 2020 - cover1
PCOC - Spring 2020 - cover2
PCOC - Spring 2020 - 3
PCOC - Spring 2020 - 4
PCOC - Spring 2020 - 5
PCOC - Spring 2020 - 6
PCOC - Spring 2020 - President’s Message
PCOC - Spring 2020 - 8
PCOC - Spring 2020 - EVP Message
PCOC - Spring 2020 - The Benefits of Being a PCOC Member
PCOC - Spring 2020 - 11
PCOC - Spring 2020 - Details About the Future of Pest Control Expo
PCOC - Spring 2020 - 13
PCOC - Spring 2020 - Surviving a Technology Conversion: 10 Tech Upgrade Tips for Smooth Sailing
PCOC - Spring 2020 - 15
PCOC - Spring 2020 - 16
PCOC - Spring 2020 - 17
PCOC - Spring 2020 - 18
PCOC - Spring 2020 - 19
PCOC - Spring 2020 - Pesticide Research Must Stay Transparent and Independent
PCOC - Spring 2020 - 21
PCOC - Spring 2020 - 22
PCOC - Spring 2020 - 23
PCOC - Spring 2020 - New Technology to Control Pests with Precision-Guided Genetics
PCOC - Spring 2020 - 25
PCOC - Spring 2020 - NPMA Federal Update
PCOC - Spring 2020 - 27
PCOC - Spring 2020 - Insurance
PCOC - Spring 2020 - 29
PCOC - Spring 2020 - 30
PCOC - Spring 2020 - 31
PCOC - Spring 2020 - State Capitol Report
PCOC - Spring 2020 - 33
PCOC - Spring 2020 - 34
PCOC - Spring 2020 - 35
PCOC - Spring 2020 - 36
PCOC - Spring 2020 - Marketing
PCOC - Spring 2020 - 38
PCOC - Spring 2020 - 39
PCOC - Spring 2020 - 40
PCOC - Spring 2020 - Firm Profile
PCOC - Spring 2020 - Index to Advertisers
PCOC - Spring 2020 - cover3
PCOC - Spring 2020 - cover4
PCOC - Spring 2020 - outsert1
PCOC - Spring 2020 - outsert2
PCOC - Spring 2020 - outsert3
PCOC - Spring 2020 - outsert4
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