NC Pork Report - Fall 2017 - 20

ning on day 2, at the appearance of symptoms. The placebo group received water
alone, and both treatments continued until
all pigs were euthanized on day 8.
A general health observation was conducted twice daily on all study animals.
Any abnormality prompted the animal
caretaker to notify the staff veterinarian.
Intervention was provided by a veterinarian in consideration of the objectives of the
protocol and in compliance with SOPs on
animal care and use.
Clinical scoring and rectal temperature
collection started daily pre-challenge on
day 0 and continued daily until euthanasia
on day 8.
Average respiratory score, nasal secretion
score, depression score, and rectal temperatures were calculated for each treatment group for days 0-8.
Pigs were scored on the following scale:
Nasal Secretion Assessment
0 = Normal - moist nares, no abnormally
excessive discharge
1 = Mildly abnormal - increased serous
nasal discharge (clear)
2 = Moderately abnormal - increased viscous nasal discharge (cloudy)
3 = Severely abnormal - purulent nasal
discharge (yellow +/- blood tinged)

Respiratory Score

0 = Rate and pattern normal, no abnormal
nasal discharge
1 = Mild - slightly increased respiratory
rate, some roughness in breathing
2 = Moderate - increased respiratory rate,
some abdominal breathing
3 = Severe - increased respiratory rate with
abnormal effort, open mouth breathing,
grunting, dog sitting

Depression Score

0 = Normal - alert, active, normal appetite,
well-hydrated, coat normal
1 = Mild - moves slower than normal,
slightly rough coat, may appear lethargic
but upon stimulation appears normal
2 = Moderate - inactive, may be recumbent but is able to stand, gaunt, may be
dehydrated
3 = Severe - down or reluctant to get up,
gauntness evident, dehydrated

Any animal that died during the study was
subjected to a necropsy and required samples were collected.
Upon day 8 necropsy, individual lung
lobes were evaluated and the amount of
consolidation was recorded. Lung lesions
were differentiated by apparent etiology.
RESULTS AND DISCUSSION
Rectal temperatures followed the same
trends for each treatment group during
most of the study (Fig. 1). Each group
had a peak in average rectal temperature
on day 1 (1-day post-SIV challenge), and
a smaller peak in average temperature
on day 5 (2-days post-P. multocida challenge). The average temperatures in the
placebo group did not reduce as quickly
after the SIV challenge as the guaifenesin
treated group did. On day 2 the average
rectal temperature for the placebo group
was 103.7˚F while it was 103.3˚F in the
guaifenesin treated group (p=0.0467). On
day 3 the average rectal temperature for
the placebo group was 103.8˚F, while the
average temperature for the guaifenesin
treated group was 103.3˚F (p=0.0562).
Both treatment groups started with an
average nasal secretion score of 0 (Fig. 2).


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Table of Contents for the Digital Edition of NC Pork Report - Fall 2017

Letter From the President
Industry News
Producer Profile
Legislative Update
Profile: Brandon Hartman
Sustained Excellence in Swine Production
Youth News
Pork Checkoff Announces
Advertiser Index
NC Pork Report - Fall 2017 - Intro
NC Pork Report - Fall 2017 - cover1
NC Pork Report - Fall 2017 - cover2
NC Pork Report - Fall 2017 - 3
NC Pork Report - Fall 2017 - 4
NC Pork Report - Fall 2017 - 5
NC Pork Report - Fall 2017 - Letter From the President
NC Pork Report - Fall 2017 - 7
NC Pork Report - Fall 2017 - Industry News
NC Pork Report - Fall 2017 - 9
NC Pork Report - Fall 2017 - 10
NC Pork Report - Fall 2017 - 11
NC Pork Report - Fall 2017 - 12
NC Pork Report - Fall 2017 - 13
NC Pork Report - Fall 2017 - 14
NC Pork Report - Fall 2017 - Producer Profile
NC Pork Report - Fall 2017 - 16
NC Pork Report - Fall 2017 - 17
NC Pork Report - Fall 2017 - 18
NC Pork Report - Fall 2017 - 19
NC Pork Report - Fall 2017 - 20
NC Pork Report - Fall 2017 - 21
NC Pork Report - Fall 2017 - 22
NC Pork Report - Fall 2017 - 23
NC Pork Report - Fall 2017 - Legislative Update
NC Pork Report - Fall 2017 - 25
NC Pork Report - Fall 2017 - Profile: Brandon Hartman
NC Pork Report - Fall 2017 - 27
NC Pork Report - Fall 2017 - Sustained Excellence in Swine Production
NC Pork Report - Fall 2017 - 29
NC Pork Report - Fall 2017 - 30
NC Pork Report - Fall 2017 - 31
NC Pork Report - Fall 2017 - Youth News
NC Pork Report - Fall 2017 - 33
NC Pork Report - Fall 2017 - Pork Checkoff Announces
NC Pork Report - Fall 2017 - 35
NC Pork Report - Fall 2017 - 36
NC Pork Report - Fall 2017 - 37
NC Pork Report - Fall 2017 - Advertiser Index
NC Pork Report - Fall 2017 - cover3
NC Pork Report - Fall 2017 - cover4
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