NC Pork Report - Fall 2017 - 21

The guaifenesin treated group reduced in
average nasal secretion score more quickly than the placebo group did after each
challenge (day 3 placebo: 0.60, guaifenesin: 0.33; day 5 placebo: 0.75, guaifenesin:
0.56).
The guaifenesin treated group also showed
signs of overall resolution of nasal secretions towards the end of the study, while
the placebo group did not. Lower secretion
scores in the guaifenesin treated group
tended toward statistical significance
on day 7 (placebo: 0.75 vs guaifenesin:
0.33, p=0.0962). A statistically significant
difference was found in the average scores
on day 8 with the guaifenesin treated
group having the lower nasal secretion
scores (placebo: 0.75 vs guaifenesin: 0.13,
p=0.0089).
Both treatment groups started with average depression scores of 0 on day 0 (Fig.
3). Both groups had elevations in average
depression scores on day 1 (post-SIV
challenge) and day 4 (1-day post-P. multocida challenge). The placebo group had
a greater elevation of depression scores

106
Placebo
Guaifenesin-treated

105.5

˚Fahrenheit

105
104.5
104
103.5
103
102.5
102
101.5

Day 0

Day 1

Day 2

Day 3

Day 4

Day 5

Day 6

Day 7

Day 8

Figure 1. Average daily rectal temperature of pigs (n=10 per treatment)
challenged with SIV on d0 and P. multocida on d3.
1.2

Nasal secretion score

Nasal secretion scores were generally lower in the guaifenesin treated group than in
the placebo group. Both treatment groups
had a significant increase in nasal secretion
score average on days 1 and 2 (post-SIV
challenge), and day 4 (1-day post-P. multocida challenge). The placebo group had a
greater average nasal secretion score on
day 1 than the guaifenesin treated group
(placebo: 0.60 vs. guaifenesin: 0.44), and
on day 2 (placebo: 0.90 vs guaifenesin:
0.56). The guaifenesin treated group had
a higher average nasal secretion score on
day 4 than the placebo group (placebo:
0.89 vs guaifenesin: 1.00).

Placebo
Guaifenesin-treated

1
0.8
0.6
0.4
0.2
0

Day 0

Day 1

Day 2

Day 3

Day 4

Day 5

Day 6

Day 7

*Day 8
(p=0.0089)

Figure 2. Average nasal secretion scores of pigs (n=10 per treatment)
challenged with SIV on d0 and P. multocida on d3. Scores: 0=Normal,
1=Mildly abnormal, 2=Moderately abnormal, 3=Severely abnormal.

after the SIV challenge and the P. multocida challenge than the guaifenesin treated
group (day 1 placebo: 0.50 vs guaifenesin:
0.22; day 4 placebo: 1.22 vs guaifenesin:
1.00).
The guaifenesin treated group tended to
show a reduction in depression scores
prior to the P. multocida challenge (day 3)
while the placebo group did not (placebo:
0.60 vs guaifenesin: 0.22, p=0.1065). The
guaifenesin treated group also showed a
continual reduction in average depression
score towards the end of the study, which
reached significance on day 8, while the
placebo group did not (day 7 placebo: 0.63
vs guaifenesin: 0.22, p=0.1035; day 8 placebo: 0.63 vs guaifenesin: 0.13, p=.0406).


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Table of Contents for the Digital Edition of NC Pork Report - Fall 2017

Letter From the President
Industry News
Producer Profile
Legislative Update
Profile: Brandon Hartman
Sustained Excellence in Swine Production
Youth News
Pork Checkoff Announces
Advertiser Index
NC Pork Report - Fall 2017 - Intro
NC Pork Report - Fall 2017 - cover1
NC Pork Report - Fall 2017 - cover2
NC Pork Report - Fall 2017 - 3
NC Pork Report - Fall 2017 - 4
NC Pork Report - Fall 2017 - 5
NC Pork Report - Fall 2017 - Letter From the President
NC Pork Report - Fall 2017 - 7
NC Pork Report - Fall 2017 - Industry News
NC Pork Report - Fall 2017 - 9
NC Pork Report - Fall 2017 - 10
NC Pork Report - Fall 2017 - 11
NC Pork Report - Fall 2017 - 12
NC Pork Report - Fall 2017 - 13
NC Pork Report - Fall 2017 - 14
NC Pork Report - Fall 2017 - Producer Profile
NC Pork Report - Fall 2017 - 16
NC Pork Report - Fall 2017 - 17
NC Pork Report - Fall 2017 - 18
NC Pork Report - Fall 2017 - 19
NC Pork Report - Fall 2017 - 20
NC Pork Report - Fall 2017 - 21
NC Pork Report - Fall 2017 - 22
NC Pork Report - Fall 2017 - 23
NC Pork Report - Fall 2017 - Legislative Update
NC Pork Report - Fall 2017 - 25
NC Pork Report - Fall 2017 - Profile: Brandon Hartman
NC Pork Report - Fall 2017 - 27
NC Pork Report - Fall 2017 - Sustained Excellence in Swine Production
NC Pork Report - Fall 2017 - 29
NC Pork Report - Fall 2017 - 30
NC Pork Report - Fall 2017 - 31
NC Pork Report - Fall 2017 - Youth News
NC Pork Report - Fall 2017 - 33
NC Pork Report - Fall 2017 - Pork Checkoff Announces
NC Pork Report - Fall 2017 - 35
NC Pork Report - Fall 2017 - 36
NC Pork Report - Fall 2017 - 37
NC Pork Report - Fall 2017 - Advertiser Index
NC Pork Report - Fall 2017 - cover3
NC Pork Report - Fall 2017 - cover4
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