Bold Voices - April 2011 - (Page 14)

PRACTICE AT THE BEDSIDE Lower Serotonin, TPH2 Linked to SIDS study associates sudden infant death syndrome (SIDS) with lower levels of serotonin and tryptophan hydroxylase (TPH2), a fi nding consistent with a disorder of medullary serotonin deficiency among control groups. According to “Brainstem Serotonergic Deficiency in Sudden Infant Death Syndrome” in the Feb. 3, 2010 Journal of the American Medical Association, SIDS may result from abnormalities in brainstem control of autonomic function and breathing during a baby’s critical development period. The study fi nds abnormalities of serotonin or 5-hydroxytryptamine (5-HT), a receptor binding in regions of the medulla oblongata, were reported in babies dying of SIDS. In a related HealthDay article, Hannah C. Kinney of Children’s Hospital Boston and pathology professor at Harvard Medical School, Boston, and colleagues report serotonin levels 26 percent lower among 35 babies who died of SIDS than of known causes. They found TPH2, an enzyme that helps make serotonin, to be 22 percent lower in SIDS babies. A SIDS may result from abnormal brainstem control during a baby’s critical development period. Rachel Y. Moon, SIDS researcher at the Goldberg Center for Community Pediatric Health at Children’s National Medical Center, Washington, D.C., suspects that lack of serotonin hampers a baby’s ability to wake up because of lack of oxygen or other health hazard. Research should identify babies who suffer from a natural lack of serotonin, says Moon, who adds, “That would be the goal, because then we would be better able to target messaging.” In a Dec. 8 HealthDay article, Rachel Y. Moon, Goldberg Center for Community Pediatric Health, Children’s National Medical Center, Washington, D.C., recommends parents follow these guidelines to help prevent SIDS: • Place babies on their backs to sleep. SIDS has dropped more than half since this recommendation was issued in 1992, according to the Nemours Foundation. • Place babies on a firm sleeping surface with a tightly fitted sheet. Don’t use a pillow, quilt or other soft surface. • Dress babies in light clothing for sleep and keep the room at a comfortable temperature. • Give babies a pacifier for sleep. Studies show lower likelihood of SIDS among babies using pacifiers. “We think it may change the baby’s arousal threshold or the way the baby breathes,” Moon says. As Technology Advances: 2011 Distinguished Research Lecture Monday, May 2, 2:15-3:30 p.m. With wry observations that range from a golf course to a house of ill repute, Marjorie Funk’s Distinguished Research Lecture examines the safe and appropriate use of technology, its equitable distribution and the human-machine interface. Funk’s studies emphasize the clinical application of monitoring — how nurses use it and how patients benefit. 14 www.aacnboldvoicesonline.org APRIL 2011 http://jama.ama-assn.org/content/303/5/430.abstract http://jama.ama-assn.org/content/303/5/430.abstract http://consumer.healthday.com/Article.asp?AID=642503 http://www.childrenshospital.org/cfapps/research/data_admin/Site164/mainpageS164P0.html http://www.childrenshospital.org/cfapps/research/data_admin/Site164/mainpageS164P0.html http://www.childrenshospital.org/ http://hms.harvard.edu/hms/home.asp http://www.childrensnational.org/research/faculty/bios/cccr/moon_r.aspx http://www.childrensnational.org/about/CentersofExcellence/goldberg.aspx http://www.childrensnational.org/about/CentersofExcellence/goldberg.aspx http://www.aacnboldvoicesonline.org

Table of Contents for the Digital Edition of Bold Voices - April 2011

Front/Digital Edition Viewing Guide
Another Angle
AACN Boards and Contact Information
NTI Checklist: Things to Do in April
API: An Advanced Practice Conference Within the NTI
Healthcare Technology Solutions
Pazopanib Provides Promise for Patients with Advanced Thyroid Cancer
Snuff Out Burnout to Retain Nurses
How to Improve EOL Care
Closely Spaced Pregnancies Pose Autism Risk
Late-Preterm Infants Risk Hospitalization
Lower Serotonin, TPH2 Linked to SIDS
Early Abuse, a Type 2 Diabetes Predictor in Women
In Our Journals
CCRN-E Initial Certification Validates Tele-ICU Knowledge
National Volunteer Week
Critical Care Exposition
Navigate NTI, Digital Style
Letters
From the President
Back

Bold Voices - April 2011

Bold Voices - April 2011 - Front/Digital Edition Viewing Guide (Page Cover1)
Bold Voices - April 2011 - Front/Digital Edition Viewing Guide (Page Cover2)
Bold Voices - April 2011 - Another Angle (Page 3)
Bold Voices - April 2011 - AACN Boards and Contact Information (Page 4)
Bold Voices - April 2011 - NTI Checklist: Things to Do in April (Page 5)
Bold Voices - April 2011 - NTI Checklist: Things to Do in April (Page 6)
Bold Voices - April 2011 - API: An Advanced Practice Conference Within the NTI (Page 7)
Bold Voices - April 2011 - Healthcare Technology Solutions (Page 8)
Bold Voices - April 2011 - Healthcare Technology Solutions (Page 8a)
Bold Voices - April 2011 - Healthcare Technology Solutions (Page 8b)
Bold Voices - April 2011 - Pazopanib Provides Promise for Patients with Advanced Thyroid Cancer (Page 9)
Bold Voices - April 2011 - Snuff Out Burnout to Retain Nurses (Page 10)
Bold Voices - April 2011 - How to Improve EOL Care (Page 11)
Bold Voices - April 2011 - Closely Spaced Pregnancies Pose Autism Risk (Page 12)
Bold Voices - April 2011 - Late-Preterm Infants Risk Hospitalization (Page 13)
Bold Voices - April 2011 - Lower Serotonin, TPH2 Linked to SIDS (Page 14)
Bold Voices - April 2011 - Early Abuse, a Type 2 Diabetes Predictor in Women (Page 15)
Bold Voices - April 2011 - In Our Journals (Page 16)
Bold Voices - April 2011 - CCRN-E Initial Certification Validates Tele-ICU Knowledge (Page 17)
Bold Voices - April 2011 - National Volunteer Week (Page 18)
Bold Voices - April 2011 - Critical Care Exposition (Page 19)
Bold Voices - April 2011 - Navigate NTI, Digital Style (Page 20)
Bold Voices - April 2011 - Letters (Page 21)
Bold Voices - April 2011 - From the President (Page 22)
Bold Voices - April 2011 - From the President (Page Cover3)
Bold Voices - April 2011 - Back (Page Cover4)
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