Bold Voices - December 2017 - 11

AT THE BEDSIDE

New Assay Can Distinguish
Bacterial From Viral Infections
and 54 indeterminate reference standard diagnoses."

Distinguishing Between Bacterial and Viral Infections
Test
Assay
CRP
Procalcitonin

Sensitivity
93.8%
88.2%
63.1%

Specificity
89.8%
73.2%
82.3%

Based on the strong performance of the new test, the
study recommends additional research to support decision-making in clinical settings. "Taken together with the
high performance observed in other independent studies,
these data support a new effective tool to help clinicians
avoid missing bacterial infections or overusing antibiotics,"
the study adds.
REFERENCE: Srugo I, Klein A, Stein M, et al. Validation of a novel assay to distinguish
bacterial and viral infections [published online September 13, 2017]. Pediatrics.
doi:10.1542/peds.2016-3453.

FDA Clears MRI System
for Premature Babies

A

new magnetic resonance imaging (MRI) system lets
premature babies stay in the neonatal ICU, which
eliminates the challenges and safety risks of transporting critically ill neonates to other areas of the hospital for
imaging.
"FDA Clears First Neonatal Magnetic Resonance
Imaging Device," a news release from the Food and Drug
Administration, explains that the Embrace Neonatal MRI
System is specifically designed to scan the heads of premature
babies weighing from 1 to 4.5 kg with head circumferences
up to 38 cm.
Clinicians put the baby in a temperature-controlled incubator, which is then placed in the MRI machine. If there's an
emergency, the baby can be removed from the device in less
than 30 seconds.
The MRI system can be used in the neonatal ICU, because
it "does not require a safety zone or a radiofrequency shielded
room." It is also fully enclosed, so medical device implants
are safe within close proximity and are not required to be
"MR Conditional" or "MR Safe," although it is contraindicated in preemies with metallic or electronically active
implanted devices.
Efficacy is based primarily on non-clinical testing to
avoid putting babies at risk. Image phantoms that simulated
a baby's brain were determined to be sufficient for diagnostic use by an independent board-certified radiologist,
and performance testing included a "review of electrical and
mechanical safety measures."

11

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Qualified applicants will receive consideration for
employment without regard to race, color, religion, sexual
orientation, gender identification, age, sex, marital status,
national origin, disability, genetic information, height or
weight or status as a qualified Vietnam era or special
disabled veteran, or other classification protected by law.

AACN BOLD VOICES DECEMBER 2017

A

n assay that distinguishes bacterial from viral infections in children performed effectively, providing the
potential for improved decision-making in clinical
settings.
"Validation of a Novel Assay to Distinguish Bacterial and
Viral Infections," in Pediatrics, notes the new assay outperformed C-reactive protein (CRP) and procalcitonin tests as
well as standard laboratory parameters used in routine practice. The assay measures the levels of three proteins in the
blood to determine a predictive score.
The independent, double-blind, multicenter study began
with 529 potentially eligible pediatric patients 3 months to
18 years old (with and without suspected acute infection)
at five pediatric emergency departments and two wards.
Criteria also included a fever of at least 38 degrees Celsius
and symptom duration of seven days or less. "The resulting
cohort included 361 patients, with 239 viral, 68 bacterial,


http://pediatrics.aappublications.org/content/early/2017/09/11/peds.2016-3453?sso=1&sso_redirect_count=2&nfstatus=401&nftoken=00000000-0000-0000-0000-000000000000&nfstatusdescription=ERROR%3A%20No%20local%20token&nfstatus=401&nftoken=00000000-0000-0000-0000-000000000000&nfstatusdescription=ERROR%3a+No+local+token http://pediatrics.aappublications.org/content/early/2017/09/11/peds.2016-3453?sso=1&sso_redirect_count=2&nfstatus=401&nftoken=00000000-0000-0000-0000-000000000000&nfstatusdescription=ERROR%3A%20No%20local%20token&nfstatus=401&nftoken=00000000-0000-0000-0000-000000000000&nfstatusdescription=ERROR%3a+No+local+token https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm567840.htm https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm567840.htm http://www.mclaren.org/macomb/career

Table of Contents for the Digital Edition of Bold Voices - December 2017

Another Angle
Pres Note Front Teaser
Masthead
AACN Updates Scope and Standards for Acute Care Nurse Practitioners
NTI 2018: Make Your Case for Attending and Register by December
Certification Holiday Reflections
Certified Nurses Day 2018
The Spirit of Giving: One Certified Nurse’s Contributions
Improving Joy in Work
Invest in Yourself With an AACN Scholarship
Disinfectant Use Associated With COPD in Nurses
The Joint Commission Revises NPSG 7 Requirements
Guidelines: Noninvasive Ventilation for Acute Respiratory Failure
High-Risk Vascular Surgeries and Postoperative Myocardial Infarction
FDA Clears MRI System for Premature Babies
New Assay Can Distinguish Bacterial From Viral Infections
Missions of Mercy
How Hospitals Can Save Without Sacrificing Care
DNA Cancer Screening Shows Potential
Smartphone App May Help Screen for Pancreatic Cancer
Cardiologist-Intensivist Model Improves Outcomes
Social Media: Legal and Ethical Issues
Unused Opioids May Pose Health Hazard
AACN’s Facebook Community Weighs In
Conscientious ‘Nudges’ Can Help Patients and Families
Helping ICU Patients With Spiritual Needs
In Our Journals
Transitions
President’s Note
Bold Voices - December 2017 - Cover1
Bold Voices - December 2017 - Cover2
Bold Voices - December 2017 - Pres Note Front Teaser
Bold Voices - December 2017 - Masthead
Bold Voices - December 2017 - NTI 2018: Make Your Case for Attending and Register by December
Bold Voices - December 2017 - Certified Nurses Day 2018
Bold Voices - December 2017 - The Spirit of Giving: One Certified Nurse’s Contributions
Bold Voices - December 2017 - Invest in Yourself With an AACN Scholarship
Bold Voices - December 2017 - The Joint Commission Revises NPSG 7 Requirements
Bold Voices - December 2017 - High-Risk Vascular Surgeries and Postoperative Myocardial Infarction
Bold Voices - December 2017 - New Assay Can Distinguish Bacterial From Viral Infections
Bold Voices - December 2017 - 12
Bold Voices - December 2017 - 13
Bold Voices - December 2017 - How Hospitals Can Save Without Sacrificing Care
Bold Voices - December 2017 - Smartphone App May Help Screen for Pancreatic Cancer
Bold Voices - December 2017 - Social Media: Legal and Ethical Issues
Bold Voices - December 2017 - Unused Opioids May Pose Health Hazard
Bold Voices - December 2017 - 18
Bold Voices - December 2017 - 19
Bold Voices - December 2017 - Transitions
Bold Voices - December 2017 - 21
Bold Voices - December 2017 - President’s Note
Bold Voices - December 2017 - Cover3
Bold Voices - December 2017 - Cover4
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