ASHRAE Journal - November 2019 - 52

ASHRAE - CELEBRATING 125 YEARS

components. Specialty firms
Figure 7 (a) Unidirectional Flow; (b) Nonunidirectional Flow; (c) Mixed Flow;26 (d) Crossflow Laminar Flow;
focused on development of clean(e) Combination Flow Laminar Flow; (d - e) from ASHRAE 1967 Handbook
room walls, floors, doors and
windows that met the needs of the
A
application owner. Designs were
binned into those using unidirectional airflow and those needing
less clean spaces where nonunidirectional airflow would suffice.
A variant of nonunidirectional
airflow was also coined using the
term mixed airflow (Figure 7).26
As the new cleanroom industry
B
C
matured, new products, including fan filter units that combined
small power fans with advanced
HEPA and ULPA filters integrated
into a single product, were being
marketed, and "turnkey" cleanroom companies were offering
complete services to all of the
major application users.
D
E
Some of the more innovative
changes in cleanrooms were the
development of isolation technology using barriers (restrictive
access barrier system, RABS) and
minienvironments.* Cleanroom
operators understood that cleanroom space was expensive, and
minimizing the spaces that need
a control particle concentration
The use of minienvironments is now commonplace in
could reduce the overall capital cost of their operasemiconductors, flat panel display, disk drives and other
tions. Pharmaceutical facilities started to isolate
microelectronics applications.
spaces by sterility requirements with nonsterile and
sterile designs. Barrier technology systems must
ASHRAE and Cleanrooms
be designed to fit the specific application and can
ASHRAE first introduced the application of cleanbe highly customized to allow the tasks required to
rooms in its 1964 Guide and Data Book (later to become the
accomplish the process needs. Applications vary
ASHRAE Handbook) in a chapter covering laboratories,
widely based on product, process equipment and
engine test facilities, computer rooms and cleanrooms.
throughput volume. Barrier technology systems may
This first instance provided some general guidance
also be designed for applications requiring operator
under the oversight of the Industrial Air Conditioning
protection from high-potency and cytotoxic comTechnical Committee. Since the initial introduction
pounds while maintaining a sterile internal environin 1964, ASHRAE has continued to publish guidance
ment. (ASHRAE, 2018)1
*This excludes isolation technology such as glove boxes or flexible film isolators (e.g. Trexler Isolators) which are not considered a cleanroom in the context of this article.

52

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N O V E M B E R 2 0 19



ASHRAE Journal - November 2019

Table of Contents for the Digital Edition of ASHRAE Journal - November 2019

Contents
ASHRAE Journal - November 2019 - Intro
ASHRAE Journal - November 2019 - Cover1
ASHRAE Journal - November 2019 - Cover2
ASHRAE Journal - November 2019 - 1
ASHRAE Journal - November 2019 - Contents
ASHRAE Journal - November 2019 - 3
ASHRAE Journal - November 2019 - 4
ASHRAE Journal - November 2019 - 5
ASHRAE Journal - November 2019 - 6
ASHRAE Journal - November 2019 - 7
ASHRAE Journal - November 2019 - 8
ASHRAE Journal - November 2019 - 9
ASHRAE Journal - November 2019 - 10
ASHRAE Journal - November 2019 - 11
ASHRAE Journal - November 2019 - 12
ASHRAE Journal - November 2019 - 13
ASHRAE Journal - November 2019 - 14
ASHRAE Journal - November 2019 - 15
ASHRAE Journal - November 2019 - 16
ASHRAE Journal - November 2019 - 17
ASHRAE Journal - November 2019 - 18
ASHRAE Journal - November 2019 - 19
ASHRAE Journal - November 2019 - 20
ASHRAE Journal - November 2019 - 21
ASHRAE Journal - November 2019 - 22
ASHRAE Journal - November 2019 - 23
ASHRAE Journal - November 2019 - 24
ASHRAE Journal - November 2019 - 25
ASHRAE Journal - November 2019 - 26
ASHRAE Journal - November 2019 - 27
ASHRAE Journal - November 2019 - 28
ASHRAE Journal - November 2019 - 29
ASHRAE Journal - November 2019 - 30
ASHRAE Journal - November 2019 - 31
ASHRAE Journal - November 2019 - 32
ASHRAE Journal - November 2019 - 33
ASHRAE Journal - November 2019 - 34
ASHRAE Journal - November 2019 - 35
ASHRAE Journal - November 2019 - 36
ASHRAE Journal - November 2019 - 37
ASHRAE Journal - November 2019 - 38
ASHRAE Journal - November 2019 - 39
ASHRAE Journal - November 2019 - 40
ASHRAE Journal - November 2019 - 41
ASHRAE Journal - November 2019 - 42
ASHRAE Journal - November 2019 - 43
ASHRAE Journal - November 2019 - 44
ASHRAE Journal - November 2019 - 45
ASHRAE Journal - November 2019 - 46
ASHRAE Journal - November 2019 - 47
ASHRAE Journal - November 2019 - 48
ASHRAE Journal - November 2019 - 49
ASHRAE Journal - November 2019 - 50
ASHRAE Journal - November 2019 - 51
ASHRAE Journal - November 2019 - 52
ASHRAE Journal - November 2019 - 53
ASHRAE Journal - November 2019 - 54
ASHRAE Journal - November 2019 - 55
ASHRAE Journal - November 2019 - 56
ASHRAE Journal - November 2019 - 57
ASHRAE Journal - November 2019 - 58
ASHRAE Journal - November 2019 - 59
ASHRAE Journal - November 2019 - 60
ASHRAE Journal - November 2019 - 61
ASHRAE Journal - November 2019 - 62
ASHRAE Journal - November 2019 - 63
ASHRAE Journal - November 2019 - 64
ASHRAE Journal - November 2019 - 65
ASHRAE Journal - November 2019 - 66
ASHRAE Journal - November 2019 - 67
ASHRAE Journal - November 2019 - 68
ASHRAE Journal - November 2019 - 69
ASHRAE Journal - November 2019 - 70
ASHRAE Journal - November 2019 - 71
ASHRAE Journal - November 2019 - 72
ASHRAE Journal - November 2019 - 73
ASHRAE Journal - November 2019 - 74
ASHRAE Journal - November 2019 - 75
ASHRAE Journal - November 2019 - 76
ASHRAE Journal - November 2019 - 77
ASHRAE Journal - November 2019 - 78
ASHRAE Journal - November 2019 - 79
ASHRAE Journal - November 2019 - 80
ASHRAE Journal - November 2019 - 81
ASHRAE Journal - November 2019 - 82
ASHRAE Journal - November 2019 - 83
ASHRAE Journal - November 2019 - 84
ASHRAE Journal - November 2019 - 85
ASHRAE Journal - November 2019 - 86
ASHRAE Journal - November 2019 - 87
ASHRAE Journal - November 2019 - 88
ASHRAE Journal - November 2019 - Cover3
ASHRAE Journal - November 2019 - Cover4
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