Contents 5 7 Less "Delete," More "Copy-Paste" from CRISPR Gene Editing CRISPR-Cas9 Edits the Epigenome 10 Photos courtesy of: iStock/zmeel iStock/Wavebreak iStock/Yuri_Arcurs iStock/cherezoff iStock/AlexRaths 12 15 18 Improving CRISPR Specificity CRISPR-Cpf1 May Outsnip CRISPR-Cas9 Using CRISPR as a High-Throughput Cancer Screening and Modeling Tool CRISPR Triple Checks Its Target before Cutting