ProteinSimple eBook - 3

Welcome
P

roteins are the heart and soul of functional
biology and understanding proteins is
central to understanding disease. However,
proteins are difficult to interrogate because
they are large, complex, and unique. Here at
ProteinSimple, we believe that traditional protein
analysis tools can be overly complex or
inadequate, and our goal is to make protein
analysis simpler, more quantitative, and
affordable. Ultimately, we want to help
researchers gain a better understanding
of proteins and their role in disease.
The most widely used protein analysis technique
in existence today is the Western blot, or Western,
which detects whether a specific protein is
present in a sample. The Western workflow,
unchanged since its invention in 1979, requires
many manual steps, can take up to 24 hours to
complete, and can lead to variable and

semi-quantitative results. Our Simple Western
platform is a complete reinvention of the Western
blot that we believe is a historic breakthrough for
protein research. Our Simple Western automates
the entire assay workflow and transforms the
Western into an analytical tool, enabling
researchers to determine precisely how much
of a specific protein exists in a given sample.
Protein-based therapeutics are transforming the
pharmaceutical industry and the treatment of
many diseases. The development and production
of biologics requires a variety of analytical tools to
ensure the quality and efficacy of these complex
drugs. Our iCE and MFI tools help researchers
analyze protein purity and identify contaminants
during biologics development and production.
Finally, many people today are asking how drug
treatment affects various biological pathways

and processes, and they want to look at it using a
holistic systems biology approach. Such tools are
rare and traditional tools like ELISA and even the
availble multiplex platforms have sensitivity and
specificity limitations. Our Simple Plex platform
takes a different approach to look at multiple
analytes simultaneously in a truly simple format.
In this eBook, we hope you can get some
valuable information from the articles about
these new protein analysis methods. Protein
analysis is our passion and along the way, we
hope you get to know us a little bit too. We
hope you enjoy the book.

John Proctor, Ph.D.
Vice President of Marketing
ProteinSimple eBook

Table of Contents for the Digital Edition of ProteinSimple eBook
