Sartorius eBook - 5

THE FUTURE OF DRUG DISCOVERY: LIVE 3D CELL ANALYSIS

7activestudio/Getty Images

Cell Stiffness May Indicate
Likelihood of Cancer Metastasis

E

ngineers and scientists in the United

demonstrate how cells in the interior of growing

States, Canada, and China have developed

breast tumor organoids are small and stiff, while

a technology for investigating how the

the cells on the periphery are softer and swollen

physical properties of cells within laboratory-

because they contain more water. Their studies

grown 3D breast tumor models, or organoids, can

showed how these softer, peripheral cells are

drive the tumor to become invasive. Headed by
researchers at the department of engineering,
Massachusetts Institute of Technology (MIT), the
team used a technology platform combining

ADDITIONAL CONTENT
Web article: Cell invasion is considered
to be a hallmark of malignant cancers
and plays a key role in metastasis.

confocal microscopy with optical tweezers to

GENengnews.com

|5


https://www.essenbioscience.com/en/applications/live-cell-assays/spheroid-invasion/ http://www.GENengnews.com

Sartorius eBook

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