Content Gazette - June 2020 - 4

only the dataset of picked particles and CTF estimations as inputs. Hence, CryoGAN bypasses
many cumbersome processing steps, including the delicate pose-estimation procedure. The
algorithm is completely unsupervised, does not rely on an initial volume estimate, and
requires minimal user interaction. To the best of our knowledge, CryoGAN is the first
demonstration of a deep-learning architecture able to singlehandedly perform the full singleparticle cryo-EM reconstruction procedure without prior training. This is joint work with
Harshit Gupta, Michael T. McCann, Laurène Donati.
About the presenter:
Michael Unser (M'89-SM'94-F'99) is professor and director of EPFL's
Biomedical Imaging Group, Lausanne, Switzerland. His primary area of
investigation is biomedical image processing. He is internationally
recognized for his research contributions to sampling theory, wavelets, the
use of splines for image processing, stochastic processes, and
computational bioimaging. He has published over 350 journal papers on
those topics. He is the author, with P. Tafti, of the book "An Introduction to
Sparse Stochastic Processes," Cambridge University Press, 2014.
From 1985 to 1997, he was with the Biomedical Engineering and Instrumentation Program, National
Institutes of Health, Bethesda, MD USA, conducting research on bioimaging.
Dr. Unser has served on the editorial board of most of the primary journals in his field including the
IEEE Transactions on Medical Imaging (Associate Editor-in-Chief, 2003-2005), the IEEE Transactions
on Image Processing, the Proceedings of the IEEE, and the SIAM Journal of Imaging Sciences. He is the
founding chair of the technical committee on Bio-Imaging and Signal Processing (BISP) of the IEEE
Signal Processing Society.
Prof. Unser is a Fellow of the IEEE (1999), an EURASIP Fellow (2009), and a Member of the Swiss
Academy of Engineering Sciences. He is the recipient of several international prizes including five IEEESPS Best Paper Awards and two Technical Achievement Awards from the IEEE (SPS in 2008 and EMBS
in 2010).

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JUNE 2020
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Content Gazette - June 2020

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