Vim & Vigor - Winter 2019 - UVA - 3

HEALTHY DOSE

WANT TO STAY UP TO DATE WITH THE LATEST HEALTH TIPS
AND NEWS FROM UVA HEALTH? IT'S SIMPLE. SUBSCRIBE TO
OUR BLOG AT BLOG.UVAHEALTH.COM OR LIKE US ON
FACEBOOK AT FACEBOOK.COM/UVAHEALTH.

UNHEALTHY GUT

PHOTOS BY GETTY IMAGES

Promotes Spread of
Breast Cancer

An unhealthy,
inflamed gut causes
breast cancer to
become much
more invasive
and spread more
quickly to other
parts of the body,
new lab research
from UVA Cancer
Center suggests.
Melanie Rutkowski,
PhD, of UVA Department of
Microbiology, Immunology and
Cancer Biology, found that disrupting
the microbiome of mice caused hormone receptorpositive breast cancer to become more aggressive.
Altering the microbiome, the collection of microorganisms that live in the gut and elsewhere, had dramatic
effects in the body, priming the cancer to spread.
"When we disrupted the microbiome in mice by
chronically treating them with antibiotics, it resulted in
widespread inflammation," she says. "In this inflamed
environment, tumor cells were much more able to
spread from the breast tissue into the blood and to
the lungs. This is a major site for hormone receptorpositive breast cancer to spread."
And most breast cancers-65 percent or more-
are this type, meaning their growth is fueled by a
hormone, either estrogen or progesterone. The
researchers published their findings in the journal
Cancer Research.
To learn more and keep up with the latest medical research from UVA, subscribe to the Making of
Medicine blog at makingofmedicine.virginia.edu.

HEALTH HAZARDS
of a Sweet Tooth
Experts agree that some added sugar in the diet is fine for most
people. But the average American consumes nearly 57 pounds
every year. You might think artificial sweeteners are a healthier
option, but new research shows they can increase the risk of
stroke. Learn more about this and find answers to other questions (like "Does sugar make kids hyper?") in a blog series,
Bittersweet: The Effects of Sugar. Go to uvahealth.com/sugar.

How to Prevent

ELDERLY DEPRESSION

As many as 1 in 3 U.S. adults older than 45 feel lonely, according
to a report by the AARP Foundation to explain why elderly depression is on the rise.
Loneliness, social
isolation and clinical depression can
cause and exacerbate each other,
explains Meredith
Lee, DO, a geriatric
psychiatrist at UVA
Health. So what can
we do? Ask elderly
loved ones about
people who have
passed away or
how they are feeling about an illness. Look through old photos
and listen to their stories. Learn more ways to prevent depression
at uvahealth.com/elders.

WINTE R 2019

3


http://BLOG.UVAHEALTH.COM http://www.FACEBOOK.COM/UVAHEALTH http://www.uvahealth.com/sugar http://makingofmedicine.virginia.edu http://www.uvahealth.com/elders

Vim & Vigor - Winter 2019 - UVA

Table of Contents for the Digital Edition of Vim & Vigor - Winter 2019 - UVA

Contents
Vim & Vigor - Winter 2019 - UVA - Cover1
Vim & Vigor - Winter 2019 - UVA - Cover2
Vim & Vigor - Winter 2019 - UVA - Contents
Vim & Vigor - Winter 2019 - UVA - 2
Vim & Vigor - Winter 2019 - UVA - 3
Vim & Vigor - Winter 2019 - UVA - 4
Vim & Vigor - Winter 2019 - UVA - 5
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Vim & Vigor - Winter 2019 - UVA - Cover3
Vim & Vigor - Winter 2019 - UVA - Cover4
https://www.nxtbook.com/nxtbooks/manifest/vimvigor_2020summer-uva
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