Pharmaceutical Commerce - September/October 2017 - 20

CONTENTS
2017 Cold Chain Outlook ....................................................................... 20
Vendor Directory (by alphabet) ............................................................ 23
Vendor Directory (by product or service) ............................................. 26

2017 Cold Chain Outlook
"Cold chain" now means cryogenic and ambient shipping, as well as the traditional 2-8° range
The life sciences cold-chain logistics
field, as 2017 begins to w ind dow n,
continues to expand and mutate as new
technological and regulatory concerns come
into play. While large parts of biopharma
industry management assume that cold
chain logistics is a routine activity (and one
whose cost should continually decline),
knowledgeable managers know that it is a
critical part of successfully distributing the
industry's products-and ultimately the
financial success of their undertakings.
Perhaps the most prominent new
trend is the early success of some cellular
therapy products, notably Novartis' FDA
review-committee approval of its CTL019
(tisagenlecleucel) therapy for a type of
lymphoma. It is the first so-called CAR-T
cell therapy, which depends on extracting
T cells from a patient, reworking the
cells' genetics and then re-infusing to the
same patient. CAR-T cell therapy is all
the rage in clinical research circles; many
more products are in the pipeline. If these
therapies prove out commercially, they will
translate into a demand not just for coldchain logistics to patients, but also from
patients.
That round-trip logistics activity is very
similar to what goes on in a clinical trial:
Investigational drugs go out, patient tissue,
blood or other biomaterials go back. The
clinical trial logistics component of overall
cold-chain activity is thriving, drawing
some of the major multinational logistics
providers into what has heretofore been a
focus of specialized courier services for the

most part. The competition is intensifying.
A significant part of this work involves
sub-zero (°C) shipping or even cryogenics:
whereas the large majority of most pharma
cold-chain activity has been to prevent subzero temperatures, now there are supply
chains restricted to those temperatures.
Me a nw h i l e , r o u t i n e d e l i v e r y o f
temperature-sensitive pharma products

streams along, with new technologies
appearing in packaging materials, phasechange materials (PCMs) and other
sources of cold, and the containers for bulk
shipments. The industry is getting more
comfortable with reusable containers
(setting up a reverse logistics process for
the empties once a delivery has been made);
ocean-going containers are being tailored

more closely to life sciences needs; and
more active (powered) container designs
are appearing.
On the regulatory front, the dominant
trend is the rising importance of good
distribution practices (GDPs) for CRT
shipping-in other words, nearly
everything except cold chain shipments.
This is proving to be a boost for the use

Fig. 1. CSafe's unit-load devices ready for placement in an aircraft cargo hold. Credit: CSafe

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Table of Contents for the Digital Edition of Pharmaceutical Commerce - September/October 2017

Table of Contents
Pharmaceutical Commerce - September/October 2017 - Cover1
Pharmaceutical Commerce - September/October 2017 - Cover2
Pharmaceutical Commerce - September/October 2017 - Table of Contents
Pharmaceutical Commerce - September/October 2017 - 4
Pharmaceutical Commerce - September/October 2017 - 5
Pharmaceutical Commerce - September/October 2017 - 6
Pharmaceutical Commerce - September/October 2017 - 7
Pharmaceutical Commerce - September/October 2017 - 8
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Pharmaceutical Commerce - September/October 2017 - 11
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Pharmaceutical Commerce - September/October 2017 - 15
Pharmaceutical Commerce - September/October 2017 - 16
Pharmaceutical Commerce - September/October 2017 - 17
Pharmaceutical Commerce - September/October 2017 - 18
Pharmaceutical Commerce - September/October 2017 - 19
Pharmaceutical Commerce - September/October 2017 - 20
Pharmaceutical Commerce - September/October 2017 - 21
Pharmaceutical Commerce - September/October 2017 - 22
Pharmaceutical Commerce - September/October 2017 - 23
Pharmaceutical Commerce - September/October 2017 - 24
Pharmaceutical Commerce - September/October 2017 - 25
Pharmaceutical Commerce - September/October 2017 - 26
Pharmaceutical Commerce - September/October 2017 - 27
Pharmaceutical Commerce - September/October 2017 - 28
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Pharmaceutical Commerce - September/October 2017 - 34
Pharmaceutical Commerce - September/October 2017 - Cover3
Pharmaceutical Commerce - September/October 2017 - Cover4
https://www.nxtbook.com/nxtbooks/pharmcomm/202006
https://www.nxtbook.com/nxtbooks/pharmcomm/202003
https://www.nxtbook.com/nxtbooks/pharmcomm/201911
https://www.nxtbook.com/nxtbooks/pharmcomm/201909
https://www.nxtbook.com/nxtbooks/pharmcomm/201906
https://www.nxtbook.com/nxtbooks/pharmcomm/201903
https://www.nxtbook.com/nxtbooks/pharmcomm/201811
https://www.nxtbook.com/nxtbooks/pharmcomm/201809
https://www.nxtbook.com/nxtbooks/pharmcomm/201806
https://www.nxtbook.com/nxtbooks/pharmcomm/20180304
https://www.nxtbook.com/nxtbooks/pharmcomm/20171112
https://www.nxtbook.com/nxtbooks/pharmcomm/20170910
https://www.nxtbook.com/nxtbooks/pharmcomm/20170708
https://www.nxtbook.com/nxtbooks/pharmcomm/20170506
https://www.nxtbook.com/nxtbooks/pharmcomm/20170304
https://www.nxtbook.com/nxtbooks/pharmcomm/20170102
https://www.nxtbook.com/nxtbooks/pharmcomm/20161112
https://www.nxtbook.com/nxtbooks/pharmcomm/20160910
https://www.nxtbook.com/nxtbooks/pharmcomm/20160708
https://www.nxtbook.com/nxtbooks/pharmcomm/20160506
https://www.nxtbook.com/nxtbooks/pharmcomm/20160304
https://www.nxtbook.com/nxtbooks/pharmcomm/20160102
https://www.nxtbook.com/nxtbooks/pharmcomm/20151112
https://www.nxtbook.com/nxtbooks/pharmcomm/20150910
https://www.nxtbook.com/nxtbooks/pharmcomm/20150708
https://www.nxtbook.com/nxtbooks/pharmcomm/20150506
https://www.nxtbook.com/nxtbooks/pharmcomm/20150304
https://www.nxtbook.com/nxtbooks/pharmcomm/20150102
https://www.nxtbook.com/nxtbooks/pharmcomm/20141112
https://www.nxtbook.com/nxtbooks/pharmcomm/coldchaindirectory2014
https://www.nxtbook.com/nxtbooks/pharmcomm/20140910
https://www.nxtbook.com/nxtbooks/pharmcomm/20140708
https://www.nxtbook.com/nxtbooks/pharmcomm/20140506
https://www.nxtbook.com/nxtbooks/pharmcomm/20140304
https://www.nxtbook.com/nxtbooks/pharmcomm/20140102
https://www.nxtbook.com/nxtbooks/pharmcomm/dataservicedirectory
https://www.nxtbook.com/nxtbooks/pharmcomm/20131112
https://www.nxtbook.com/nxtbooks/pharmcomm/20130910_hubreport
https://www.nxtbook.com/nxtbooks/pharmcomm/20130910
https://www.nxtbook.com/nxtbooks/pharmcomm/20130708
https://www.nxtbook.com/nxtbooks/pharmcomm/20130506
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https://www.nxtbook.com/nxtbooks/pharmcomm/20130304
https://www.nxtbook.com/nxtbooks/pharmcomm/20130102
https://www.nxtbook.com/nxtbooks/pharmcomm/20121112
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https://www.nxtbook.com/nxtbooks/pharmcomm/20120708
https://www.nxtbook.com/nxtbooks/pharmcomm/20120506
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https://www.nxtbook.com/nxtbooks/pharmcomm/20111112
https://www.nxtbook.com/nxtbooks/pharmcomm/20110910
https://www.nxtbook.com/nxtbooks/pharmcomm/20110708
https://www.nxtbook.com/nxtbooks/pharmcomm/20110506
https://www.nxtbook.com/nxtbooks/pharmcomm/20110304
https://www.nxtbook.com/nxtbooks/pharmcomm/20110102
https://www.nxtbook.com/nxtbooks/pharmcomm/20101112
https://www.nxtbook.com/nxtbooks/pharmcomm/20100910
https://www.nxtbook.com/nxtbooks/pharmcomm/20100708
https://www.nxtbook.com/nxtbooks/pharmcomm/20100506
https://www.nxtbook.com/nxtbooks/pharmcomm/201004
https://www.nxtbook.com/nxtbooks/pharmcomm/201003
https://www.nxtbook.com/nxtbooks/pharmcomm/20100102
https://www.nxtbook.com/nxtbooks/pharmcomm/20091112
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