Pharmacy Perspectives - Winter/Spring 2015 - (Page 6)
WINTER/SPRING
SCREENING
POTENTIAL DRUGS
- THOUSANDS OF COMPOUNDS AT A TIME
R EPR I NTED FROM A N A RTICLE I N TH E AU ROR A SENTI NEL
BY BR ANDON JOHN ANSSON
P
erched on a high lab table
at the school of pharmacy
sits what looks like a futuristic copy machine with a
bright blue light emanating from the middle. The device
lets researchers study thousands of
compounds at a time that could one
day turn into drugs.
On a recent afternoon, Dr. Brian Reid,
director of the school's high-throughput
screening core facility, used the device
to study various compounds interacting
with the heart. The research is part of a
collaboration with cardiology researchers aimed at finding drugs to combat a
particular form of heart failure.
"Heart failure can be roughly
divided into two types. There are very
good drugs for one form, and they're
inexpensive and extend millions of
patients' lives. But for the second
type, which represents roughly half
of heart failure patients, there really
aren't any good options. We are looking for new therapies for this second
type," Reid said.
That kind of science - partnerships between disciplines to look for
medical breakthroughs - is something
state officials want to see more of, and
research that can one day be marketable enough to create jobs.
Last year, the Colorado Office
Dr. Brian Reid in the high-throughput screening facility
6
CU Skaggs School of Pharmacy and Pharmaceutical Sciences
of Economic Development and
International Trade (OEDIT) announced more than $3 million in
grants aimed at helping academic
researchers and bioscience companies take research from labs like
those at our school to market. In the
case of researchers at our school, the
$410,000 grant we received is aimed
at helping the high throughput/
content screening core facility for
drug discovery, which more than
100 researchers and companies have
used to advance science and help to
secure intellectual property, according to OEDIT.
Dr. David Ross, chairman of the
department of pharmaceutical
sciences said this particular research is
important because it allows scientists
to compare thousands of compounds
quickly against a specific disease. That
leads to the discoveries that can one
day become life-saving drugs.
Grants like the one from OEDIT
are crucial to making sure those
breakthroughs can one day benefit
the state, he said.
"If we didn't capitalize on those,
then those opportunities would go
out of state," he said. This provides a
way to optimize the resources that
you need to capitalize on those innovations within the state of Colorado."
April Giles, president and CEO of
the Colorado BioScience Association,
said that from the industry's perspective, the grants are hugely important
because they can bridge the gap
between the research lab and the
market place.
"This allows them to really look at
drug discovery in a way that pharmacies or biosciences companies would
utilize in a commercial way," she said.
RESEARCH ON THE
RUNWAY RECAP
In September, visiting research
associate Georgia Charkoftaki, PhD,
and designer Lilian Kong traveled to
MIT for the Descience Competition
where science and fashion collaborated to create a science-inspired
look for the runway. Georgia's look
focused on discovering a drug
and delivery mechanism for lupus
nephritis. Their entry garnered a
fifth place finish in the People's
Choice category and received a
"shout-out" from local NBC Affiliate
9NEWS. "It was a once in a lifetime
type of experience and an amazing
show," says Georgia. The look,
together with the 3-D jewelry, will
be displayed in the Health Sciences
Library at the Anschutz Medical
Campus in the near future, so stay
tuned for the unveiling.
Table of Contents for the Digital Edition of Pharmacy Perspectives - Winter/Spring 2015
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Pharmacy Perspectives - Winter/Spring 2015
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Pharmacy Perspectives - Winter/Spring 2015 - In this Issue (Page 16)
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