Magnetics Business & Technology - July/August 2021 - 19

RESEARCH & DEVELOPMENT
In Phase 1, the team identified a genetically targeted magnetic
stimulation technology that can achieve cell-type specific stimulation
with a spatial resolution defined by the distribution of genetically
modified cells (< 1mm) and with a temporal resolution
approaching 10 ms, as depicted in Fig. 1. Their work showed a
more than 10-fold improvement in temporal resolution compared
to state-of-the-art magnetogenetic stimulation.
technology that achieved targeted and non-invasive delivery of
viruses in mice, demonstrating fast magnetic stimulation in mammalian
cells; also in viral delivery using magnetic iron oxide nanocrystal
clusters of core/shell with high magnetic heating efficiency
and magnetothermal multiplexing.
In Phase 2, the team aims to advance its work further toward the
goal of reaching demonstration in humans in Phase 3. Among the
goals for Phase 3 are to accomplish non-surgical reads, writes
with magnetogenetics, and to demonstrate closed-loop brain-tobrain
MOANA link in humans.
Other N3 projects also involve magnetic science and technology:
*
The PARC team, under principal investigator Dr. Krishnan
Thyagarajan, aims to develop a completely noninvasive
acousto-magnetic device for writing to the brain. Their approach
pairs ultrasound waves with magnetic fields to generate localized
electric currents for neuromodulation. The hybrid approach offers
the potential for localized neuromodulation deeper in the brain.
MOANA project Fig. 2
They also accomplished, as depicted in Fig. 2, successful tapeout
of the MOANA chiplet and design of a prototype flexible patch
for imaging a brain phantom through a 5mm skull phantom. Photon
counting ability met the design specifications for an integrated
ToFF-DOT system.
Among other accomplishments in Phase 1, were efforts in write
*
The Teledyne team, under principal investigator Dr.
Patrick Connolly, aims to develop a completely noninvasive, integrated
device that uses micro optically pumped magnetometers
to detect small, localized magnetic fields that correlate with neural
activity. The team will use focused ultrasound for writing to neurons.
For
more information, see www.darpa.mil.
ALTIM2047_MagneticsBusiness&Technology_7,375x4,75_vecto.indd 1
www.MagneticsMag.com
12/01/2021 14:35
July/August 2021 * Magnetics Business & Technology 19
http://www.darpa.mil https://www.metrolab.com/ http://www.MagneticsMag.com

Magnetics Business & Technology - July/August 2021

Table of Contents for the Digital Edition of Magnetics Business & Technology - July/August 2021

Magnetics Business & Technology - July/August 2021
Editor’s Choice/ Features
Major Automakers Transform Design & Manufacturing Operations on Accelerated Path to e-Propulsion – Part 2 of 2
Luxury Auto Maker Bentley Goes After Magnet Materials & Manufacturing Advancements
Magnetism Plays Key Roles in DARPA Research to Develop Brain-Machine Interface without Surgery
Research & Development
Product News
Industry News
Events Calendar/ Advertising Index
Toshiba’s New Magnetic Material Improves Motor Energy Conversion Efficiency
Visions
Magnetics Business & Technology - July/August 2021 - Magnetics Business & Technology - July/August 2021
Magnetics Business & Technology - July/August 2021 - Cover2
Magnetics Business & Technology - July/August 2021 - 3
Magnetics Business & Technology - July/August 2021 - Editor’s Choice/ Features
Magnetics Business & Technology - July/August 2021 - 5
Magnetics Business & Technology - July/August 2021 - Major Automakers Transform Design & Manufacturing Operations on Accelerated Path to e-Propulsion – Part 2 of 2
Magnetics Business & Technology - July/August 2021 - 7
Magnetics Business & Technology - July/August 2021 - 8
Magnetics Business & Technology - July/August 2021 - 9
Magnetics Business & Technology - July/August 2021 - 10
Magnetics Business & Technology - July/August 2021 - 11
Magnetics Business & Technology - July/August 2021 - Luxury Auto Maker Bentley Goes After Magnet Materials & Manufacturing Advancements
Magnetics Business & Technology - July/August 2021 - 13
Magnetics Business & Technology - July/August 2021 - 14
Magnetics Business & Technology - July/August 2021 - 15
Magnetics Business & Technology - July/August 2021 - Research & Development
Magnetics Business & Technology - July/August 2021 - 17
Magnetics Business & Technology - July/August 2021 - 18
Magnetics Business & Technology - July/August 2021 - 19
Magnetics Business & Technology - July/August 2021 - 20
Magnetics Business & Technology - July/August 2021 - 21
Magnetics Business & Technology - July/August 2021 - Product News
Magnetics Business & Technology - July/August 2021 - 23
Magnetics Business & Technology - July/August 2021 - 24
Magnetics Business & Technology - July/August 2021 - 25
Magnetics Business & Technology - July/August 2021 - Industry News
Magnetics Business & Technology - July/August 2021 - 27
Magnetics Business & Technology - July/August 2021 - 28
Magnetics Business & Technology - July/August 2021 - 29
Magnetics Business & Technology - July/August 2021 - 30
Magnetics Business & Technology - July/August 2021 - 31
Magnetics Business & Technology - July/August 2021 - Events Calendar/ Advertising Index
Magnetics Business & Technology - July/August 2021 - 33
Magnetics Business & Technology - July/August 2021 - Visions
Magnetics Business & Technology - July/August 2021 - Cover3
Magnetics Business & Technology - July/August 2021 - Cover4
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