Magnetics Business & Technology - September/October 2022 - 31

INDUSTRY NEWS
Blacktrace Rolls Out Particle Works to Automate Nanoparticle Engineering
In concert with the growing demand for greater volumes of
biotech nanoparticles, Particle Works has been launched as a
new source for the automation of nanoparticle engineering and
production. The company says that magnetic nanoparticles
could be candidates for its process to encapsulate or template
lipid nanoparticles (LNPs) but so far have not been tested in
their Automated Nanoparticle System. Blacktrace Holdings Ltd,
a UK firm which specializes in commercializing scientific developments,
recently branded Particle Works as a spinout from its
Dolomite Microfluidics business unit.
LNPs are a versatile formulation technology used by drug
development teams to deliver a variety of molecules, peptides,
and biologicals. Particle Works' particle engineering platforms
are set to revolutionize the way customers discover, develop
and scale-up particle production for a wide range of applications,
says the company. Previously, nanoparticles such as
liposomes, LNPs and polymer-based nanoparticles have been
produced using batch methods that can be inconsistent and
difficult to control.
Particle Works, however, uses microfluidic technologies to
create pioneering systems capable of consistent and tuneable
particle generation, enabling the manufacturing process to be
more stable and efficient, with a lower chance of particle damage,
further reducing time of development cycles. The brand
will initially focus on enhancing drug encapsulation and vaccine
delivery.
" As leaders in the field of particle technology, " explains Lee
Jeffries, managing director, " we understand the needs of our
customers, and Particle Works is the direct result of the growing
demand for reliable and scalable solutions for nanoparticle
production.
The tremendous success of mRNA-lipid nanoparticle (LNP)based
vaccines during the COVID-19 pandemic has led to
further explosive growth in development and created new opportunities
in this area. The unprecedented speed of developwww.MagneticsMag.com
ment
of the COVID-19 LNP-based vaccines was, to a large
extent, built upon foundational work performed over the last
10-15 years in LNP platform development, says the company.
For more info, see www.particle-works.com.
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September/October 2022 * Magnetics Business & Technology 31
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Magnetics Business & Technology - September/October 2022

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