Magnetics Business & Technology - September/October 2024 - 4
EDITOR'S CHOICE
Monarch Mag Kit from New England Biolabs Detects DNA/
RNA Viruses
New England Biolabs
has added a new extraction
kit to its nucleic acid
purification portfolio that
uses a process based on
magnetic beads to extract
viral RNA and DNA. The
new Monarch Mag Viral
DNA/RNA Extraction Kit
enhances recovery of low
amounts of viral nucleic
acid to enable highly sensitive
detection.
" Isolating viral nucleic acids is crucial for several areas of life sciences research, including
viral genome sequencing, infectious disease detection, and wastewater surveillance, " said
James Deng, senior product marketing manager for NEB's nucleic acid purification product
line. " These methods require high sensitivity to detect the canonically low amount of virus
in a sample, and high throughput to meet the demands of infectious disease testing and
surveillance. "
" We've addressed these challenges with a viral nucleic acid purification kit that enables
some of the highest sensitivity in detection commercially available, which we've tested with
a wide range of virus types. We have also designed the kit for hands-free use on various
automated instrument platforms to enable more flexibility and versatility, " stated Anagha
Kadam, applications & product development scientist at NEB.
Using the company's magnetic bead-based process to
extract viral RNA and DNA reproducibly and efficiently,
it enables scale up for high-throughput automation.
The kit is compatible with the most common sample
types for extracting viral nucleic acids including saliva,
respiratory swab samples and, following an enrichment
step, wastewater samples.
Highly-sensitive detection, following extraction of viral
nucleic acid in samples containing few target molecules, is achieved through a combination
of a magnetic bead-based method, an optimized buffer chemistry and a simplified extraction
procedure, in which carrier RNA is utilized as a co-precipitant to enhance the recovery
of low amounts of viral nucleic acid. Furthermore, customers can elute the purified RNA in
low elution volumes, making the kit a desirable choice for various downstream applications.
NEB produces a portfolio of magnetic-bead
based purification products including magnetic
particle processors.
In contrast to spin column-based nucleic
acid purification methods, the bead-based
technology offers researchers greater scalability
and flexibility in moving from manual
processing of viral samples to a handsfree,
automatable approach. The kit works
on a variety of automation instrument
platforms, allowing researchers the flexibility
to use their preferred workflows and
instrumentations, including the company's
KingFisher Flex magnetic particle processor,
and the Agilent Bravo and MGISP
liquid handler platforms.
Based in Ipswich, Massachusetts and established
in the mid 1970's, NEB specializes
in the discovery and production of enzymes for molecular biology applications, producing
a large selection of recombinant and native enzymes for genomic research. For more info,
see www.neb.com.
4 Magnetics Business & Technology * September/October 2024
Volume 23, Issue 5
Editor & Publisher
David Webster
Contributing Editor
Dr. Stan Trout
Director of Operations and
Support Services
Ross Webster
Director of Sales and Content
Scott Webster
Design & Layout
Scott Webster
Administration
Marsha Grillo
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Magnetics Business & Technology - September/October 2024
Table of Contents for the Digital Edition of Magnetics Business & Technology - September/October 2024
Contents
Magnetics Business & Technology - September/October 2024 - Cover1
Magnetics Business & Technology - September/October 2024 - Cover2
Magnetics Business & Technology - September/October 2024 - Contents
Magnetics Business & Technology - September/October 2024 - 4
Magnetics Business & Technology - September/October 2024 - 5
Magnetics Business & Technology - September/October 2024 - 6
Magnetics Business & Technology - September/October 2024 - 7
Magnetics Business & Technology - September/October 2024 - 8
Magnetics Business & Technology - September/October 2024 - 9
Magnetics Business & Technology - September/October 2024 - 10
Magnetics Business & Technology - September/October 2024 - 11
Magnetics Business & Technology - September/October 2024 - 12
Magnetics Business & Technology - September/October 2024 - 13
Magnetics Business & Technology - September/October 2024 - 14
Magnetics Business & Technology - September/October 2024 - 15
Magnetics Business & Technology - September/October 2024 - 16
Magnetics Business & Technology - September/October 2024 - 17
Magnetics Business & Technology - September/October 2024 - 18
Magnetics Business & Technology - September/October 2024 - 19
Magnetics Business & Technology - September/October 2024 - 20
Magnetics Business & Technology - September/October 2024 - 21
Magnetics Business & Technology - September/October 2024 - 22
Magnetics Business & Technology - September/October 2024 - 23
Magnetics Business & Technology - September/October 2024 - 24
Magnetics Business & Technology - September/October 2024 - 25
Magnetics Business & Technology - September/October 2024 - 26
Magnetics Business & Technology - September/October 2024 - 27
Magnetics Business & Technology - September/October 2024 - 28
Magnetics Business & Technology - September/October 2024 - 29
Magnetics Business & Technology - September/October 2024 - 30
Magnetics Business & Technology - September/October 2024 - 31
Magnetics Business & Technology - September/October 2024 - 32
Magnetics Business & Technology - September/October 2024 - 33
Magnetics Business & Technology - September/October 2024 - 34
Magnetics Business & Technology - September/October 2024 - Cover3
Magnetics Business & Technology - September/October 2024 - Cover4
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