Journal of Hand Surgery - June 2022 - S482

S482
Journal of Hand Surgery (Eur) 47(Supplement 1)
cognitive functions of children with brachial plexus
except orientation were found to be lower than those
of healthy children (p<0.05). Working memory and
inhibition skills, which are among the evaluated
executive functions, of children with brachial plexus
were found to be weaker than healthy children
(p<0.05).
Conclusions: Cognitive and executive functions
resulting from the interaction of multiple sensorimotor
processes are affected due to sensory involvement
and cortical changes after OBPI. It is believed
that person-centered, cognitive occupational therapy
interventions will improve the cognitive functions of
children with brachial plexus and contribute to their
learning and academic skills.
A-2311 Epidemiology of Congenital Upper Limb
Anomalies in 100 Patients: A Single Centre Study
S Raja Sabapathy and Monusha Mohan
Ganga hospital, Coimbatore, India
Objective: Epidemiological data for congenital upper
limb anomalies (CULA) is essential for health care
planning and for high quality epidemiological data.
The objective of this study is to prospectively analyze
the demographics and clinical presentation of the
first 100 consecutive patients who visited a single
centre with CULA from January 2021.
Methods: Demographic information and detailed
antenatal history was collected from 100 consecutive
patients who visited our clinics with CULA from
January 2021. The anomalies were classified using
primary diagnoses as well as according to the ObergManske-Tonkin
(OMT) classification IFSSH 2020. The
age at presentation, age at first surgery, place of
residence, number of surgeries done, birth weight,
diagnosis, associated anomalies, consanguinity of
marriage, order of pregnancy, history of infertility,
miscarriage, maternal and paternal age at conception,
prenatal history-history of fever, drug intake,
bleeding per vaginum, maternal diseases, presence
of anomaly, liquor volume in ultrasound scan, type of
delivery, postpartum history, developmental milestones
and family history for congenital anomalies.
The data was analyzed over a period of 8 months.
Binary logistic regression analysis was done to find
the relation between CULA and the factors-maternal
and paternal age at conception, consanguinity, history
of miscarriage, presence of infertility, presence of
maternal disease, positive family history for congenital
anomalies and a positive history of bleeding per
vaginum (PV) during gestation.
Results: Among 100 patients, male preponderance
(57%) noted. 81% percent of the patients were from
the state where the hospital is located and neighbouring
states. Among patients, 55% were operated
at least once. Bilateral hand involvement was seen
in 56%. The most common primary diagnoses
were Constriction Ring Sequence (18%) and
Symbrachydactyly (14%). According to the OMT
classification, 57% were malformations, 17% deformations,
14% dysplasias and 12% syndromes.
Associated anomalies noted in 58%; lower limbs
being the most commonly involved (n¼28). Among
our patients, 15% had a consanguineous marriage,
26% had a history of miscarriage and 15% had a positive
history of infertility. Bleeding PV during gestation
was reported in 7%. Oligohydramnios was present
in 11%. Polyhydramnios was reported in 2%.
Mean maternal age at conception was 26.2 years
and mean paternal age was 31.2 years. Maternal
age was in the range 25-29 years in 46% cases
whereas paternal age was in the range 30-34 years
in 36% cases. Family history of congenital anomalies
was found in 16%. Preliminary analysis using binary
logistic regression, the relation between symbrachydactyly
and bleeding PV during gestation was significant.
Relation between constriction ring sequence
and presence of maternal disease was significant.
History of miscarriage and syndactyly had significant
relation.
Conclusion: We used IFSSH classification 2020
update to determine the relative frequency of anomalies
and basic epidemiological parameters.
Statistical analysis to find relation between various
variables - relevant antenatal factors and CULA
revealed significant relation between antenatal
bleeding PV and symbrachydactyly, between maternal
disease and constriction ring sequence and
between miscarriage and syndactyly. This data will
be useful for health care planning, monitoring and
research.
A-2313 Wrist clinical and biomechanical
assessment of hEDS and HSD patients
Marta Jokiel1,2, Aleksandra Bartkowiak1,2,
Anna Wachowiak1,2, Ewa BreRborowicz1, Olga Haus3,
Aleksander Jamsheer4 and Leszek Romanowski1
1Traumatology, Orthopedics and Hand Surgery Department
Poznan University of Medical Sciences
2Physiotherapy Department Poznan University of Medical
Sciences
3Clinical Genetics Department Copernicus Torun University
4Medical Genetics Department Poznan University of
Medical Sciences
Introduction: Ehlers Danlos Syndrome (EDS) is a
genetic mutation which is responsible for protein
Journal of Hand Surgery - June 2022

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