Tumori Journal Abstract Book - October 2020 - 205

U - Oncology Nursing

205

in all contexts or finally by studies with methodological
bias. The use of bovine colostrum seems to represent an
important opportunity to prevent and / or limit the appearance of OM. Colostrum is the "milk" secreted during the
first few days after childbirth important for the health of
newborns. It contains nutrients and bioactive components,
with an immune stimulating function, growth factors and
with antimicrobial activities. The bovine one contains even
more of these elements.
Material and Methods: In the Hematology of the AUSLIRCCS of Reggio Emilia, a monocentric study was conducted with a standard design for phase II studies according
to Simon (Optimal Design), a two-step design with a cut off
after the first for ensure patient safety. The overall sample is
59 evaluable cases (step1_ 19 cases; step2_ 40 cases).

Objective: To evaluate whether the addition of 100% colostrum products to the standard of care oral hygiene protocol
can be more active than oral hygiene alone in protecting
mucous membranes from the onset of mucositis in patients
undergoing myeloablative regimen for bone marrow transplantation. We hypothesized that with the addition of colostrum to standard practice, a reduction in the incidence of
severe mucositis of 50% (from 30 to 15%) could be obtained.
Results: The study is over. The first results show that:
Severe mucositis decreased from 23.8% to 10.2%, mild
intensity mucositis are around 64%, recording a slight
increase, while the number of patients who have not developed mucositis has increased.
Conclusions: The data are very encouraging, a RCT is
now developing to confirm these results.

YEAR/STEP

2016

2017

STUDY Step 1

STUDY Final

HSCT
NO MUCOSITIS
MILD (1-2 WHO)
SEVERE (3-4 WHO)

42
8 (19,0%)
24 (57,2%)
10 (23,8%)

39
8 (20,5%)
19 (48,7%)
12 (30,8%)

19
4 (21,0%)
14 (73,7%)
1 (5,3%)

59
15 (25,4%)
38 (64,4%)
6 (10,2%)

U02*
Home Se-Cure: management of oral,
intramuscular and subcutaneous
oncological therapies at home.
Day Hospital experience - Medical
Oncology, E.O. Galliera of Genoa
Franconeri M.1, Marceca F.1, Buttiron Webber T.1, Magnani M.1,
Paciolla F.1, Patrone C.1, Cevasco I.1, Franconeri R.1, Provinciali N.1,
Defferrari C.1, Clavarezza M.1, D'Amico M.1, De Censi A.1
1

E.O. Galliera, Genova

Background: Recent studies show that patients with cancer
are more exposed to a greater risk of Covid-19 infection,
developing more severe symptoms and higher risk of death.
The fear and risks include a source of stress for patients who
have to go to the hospital for treatment. To meet their needs,
we designed the Home Se-Cure project which aims to guarantee patients the continuity of oral, intramuscular and subcutaneous cancer therapies, delivering treatment at home.
Materials and methods: The project will include patients
aged> 65 years, fragile patients with ECOG 2-3-4, living
in the neighboring areas of the hospital. We hypothesized
to perform about 8 intervention per day. The interventions
will include blood sampling, oral, intramuscular and subcutaneous therapies. The activity will be carried out during
working hours, from 7.30 to 11 for two days a week.
Nurses and oncologists will select the patients who will be
contacted by phone to schedule the appointment. The oncologist prescribes and documents the blood tests and / or home
cancer therapy to be delivered to the patient. The nurse picks

up the drugs at the hospital pharmacy and goes to the
patient's home equipped with the required PPE. Therapy can
only be taken after confirmation by telephone from the
nurse and doctor based on the result of the blood tests.
A customer satisfaction questionnaire will be administered
to patients and will be compared with those who refuse this
service or cannot access it because of geographical reasons.
Results: We expect our results to bring: reduce patient travel,
ensure continuity of therapy, avoid gatherings at the day hospital. Guarantee the safety of fragile patients by respecting
the ministerial recommendations. Avoid the stress related to
the dilemma to perform the therapies Vs risk of contagion.
Reduce access to the Emergency Room through early recognition of toxicity and non-compliant blood values.
Conclusions: By accomplishing these results we would
should achieve a better organization of the work, a reduction of the clinical risk, an improvement of the quality of
care and a greater working well-being of the staff.

U03*
Nursing phone call monitoring
may reduce the incidence of
serious adverse events during
new innovative treatments in
melanoma patients
Esposito M.R.1, Sabatelli P.2, D'Ausilio T.2, Esposito F.2, Barbieri C.2,
Simeone E.2
1

Istituto Tumori di Napoli, Napoli; 2Istituto Nazionale Tumori IRCCS
Fondazione G. Pascale, Napoli

Tumori Journal Abstract Book - October 2020

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