Tumori Journal Abstract Book - October 2020 - 89

D - COVID-19

D45
RAPID SEROLOGICAL TEST IN THE
COVID-19 ERA: OUR EXPERIENCE
Caponigro G.1, Fusco O.1, Pastorini A.1, Deligiannis P.1, Maiolani M.1,
Cubeddu A.1, Menatti E.1, Barbonetti C.2, Fregoni V.3, Stiglich F.2,
Cattalini N.4, Del Barba M.5, Bertolini A.1
1
ASST della Valtellina e Alto Lario-Oncologia Medica, Sondrio; 2ASST della
Valtellina e Alto Lario-Radioterapia, Sondrio; 3ASST della Valtellina e Alto
Lario-Breast Unit, Sondalo; 4ASST della Valtellina e Alto Lario-Direzione
Medica, sondrio; 5Parlamento Italiano, Sondrio

Background: The COVID-19 was first reported in Wuhan,
China, in December 2019 and then spread rapidly around
the world also affecting our country.
It caused many deaths, not sparing health workers. The
active detection of infection among health professionals is
essential to ensure the safety of them and to reduce the
spread of the virus.
We evaluated use of the qualitative serological test in
asymptomatic healthcare workers in the Sondrio Hospital.
Material (patients) and methods: We analyzed 220 asymptomatic healthcare workers assessed for qualitative serological test from March 2020 to date; trial is actually ongoing.
We chose qualitative NADAL® COVID-19 IgG/IgM Rapid
Test (test cassette) REF 243001N-10, by Nal Von Minden
GmbH (Germany). This is a lateral flow chromatographic

immunoassay for the qualitative detection of anti-SARSCoV-2 IgG and IgM in human whole blood, serum or plasma
specimens. The test procedure is not automated and requires
no special training or qualification. It is necessary a fingerprick blood sample and provides a qualitative result within
15 minutes. It has a high sensitivity with 94,1% and 99,2%
specificity.
Some of the subjects analyzed were also evaluated with
quantitative serological test (Diasorin test).
Results: 25/220 asymptomatic cases tested resulted positive to qualitative serological rapid test (Table 1), 5 of
which were conniving with people positive to COVID-19
but not been swabbed.
In 7/25 subject positive we had a quantitative positive IgG
response; these people are found to be positive to nasopharyngeal swab.
We have had 195/220 cases with qualitative negative
response, in 43 of which the result of the rapid test has
been confirmed by the quantitative serological test; in 152
cases the quantitative test was not carried out.
Conclusions: Rapid qualitative serological test is ready,
economic and able to identifies asymptomatic subjects
who may have developed immunity.
It could be useful as a rapid screening procedure in the
healthcare workers to identify immune or infected people
that should be isolated to reduce spread of the COVID-19.

Table 1. Clinical Characteristics of subjects.
Covid 19 unknown

Negative to qualitative

Diagnosis by qualitative

Quantitative detected+ in
qualitative + patients

Swab +

n=220

195

Covid 19 -

Confirmed - quantitative

Quantitative not detected

195

152

# only 7/25 serological test+ had a swabs detection.

D46
Psychological impact of COVID-19
emergency on health workers in
Italy: Preliminary results from an
online survey
Carapezza L.1, La Rosa V.L.2, Piazza D.3, Gebbia V.4, Martines C.5,
Commendatore O.5, Russo A.E.5, Bordonaro R.5
1
Oncologia Medica A.R.N.A.S. Garibaldi, Catania, Italy; 2Dipartimento di
Scienze della Formazione, Università degli Studi di Catania, Catania, Italy;
3
GSTU Foundation for Cancer Research, Palermo, Italy; 4Casa di Cura
La Maddalena, Palermo, Italy; 5Oncologia Medica, A.R.N.A.S. Garibaldi,
Catania, Italy

Background: COVID-19 disease quickly spread all over
the world starting from Wuhan, China in December 2019.In
Italy too, the lockdown was necessary from March to May

2020 to contain the exponential increase in infections. The
pandemic outbreak has significantly affected the psychological wellbeing of the general population. However,
according to the recent literature, healthcare workers were
subject to greater stress and emotional impact due to a number of factors: active role in assisting COVID-19 patients,
increased risk of infection, fear of infecting families, social
stigma, exhausting working conditions. For this reason, we
aimed to evaluate the psychological impact of the emergency in a group of Italian health workers.
Methods: We examined the psychological discomfort,
depression, anxiety and stress experienced by health workers in Italy during the outbreak spike through the use of
IES, BAI and BDI-II tests and compared them together
with the sample's demographic characteristics as well as
several measures strictly related to direct and indirect
Covid-19 experiences.

http://www.2019.In

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