IJT - CIR - February 2024 - 53S

Cherian et al.
53S
Adenosine Triphosphate. Adenosine Triphosphate may be produced
by microbial phosphorylation of Adenosine Phosphate.7
Impurities
Adenosine. A supplier reported that Adenosine has a purity
of ≥ 99%.8
Adenosine Triphosphate. A supplier reported the following
impurities for Adenosine Triphosphate: < 2% Adenosine
Phosphate, < 2% Adenosine diphosphate, and < .01%
methanol.9
Figure 1. Adenosine.
Disodium Adenosine Triphosphate. Disodium Adenosine Triphosphate
used in a trade name mixture sold to the cosmetic
industry was reported to be free from carcinogens, mutagens,
and reproductive toxicants (CMR) as defined by European
Union (EU) chemical regulations, and from phthalates, pesticides,
and glycol ether.10 Additional details were not provided.
Table 2. Chemical Properties of the Adenosine Ingredients in This Safety Assessment.
Property
Value
Adenosine
Physical form
Color
Odor
Molecular weight (g/mol)
Vapor pressure (mmHg @ 25°C)
Melting point (°C)
Water solubility (g/l @ 25°C)
log Kow
λmax (@ pH = 7.0; nm)
Adenosine Phosphate
Physical form
Molecular weight (g/mol)
Melting point (°C)
Water solubility (g/l)
log Kow
Adenosine Triphosphate
Physical form
Molecular weight (g/mol)
Water solubility (g/l)
log Kow
Disodium Adenosine Phosphate
Formula weight (g/mol)
log Kow
Disodium adenosine triphosphate
Formula weight (g/mol)
log Kow
Crystalline powder
White
Odorless
267.25
6.0 × 1015
235.5
5.1
1.05
14.6-15.2
Solid
347.22
195
3.31
3.1
Solid
507.18
1000
3.61 (estimated)
391.19
1.11 (estimated)
551.15
6.44 (estimated)
Reference
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IJT - CIR - February 2024

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IJT - CIR - February 2024 - Cover3
IJT - CIR - February 2024 - Cover4
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