Medical Design Briefs - May 2021 - 35

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Rose-tinted contact lenses (about 10 mm in diameter) containing gold
nanoparticles filter out problematic colors for people with red-green color
blindness. (Credit: Adapted from ACS Nano 2021, DOI: 10.1021/
acsnano.0c09657)

Thus, researchers have shifted to the development of
special tinted contact lenses. Although the prototype hotpink dyed lenses improved red-green color perception in
clinical trials, they leached dye, which led to concerns
about their safety. Gold nanocomposites are nontoxic and
have been used for centuries to produce " cranberry glass'
because of the way they scatter light. So, Ahmed Salih,
Haider Butt, and colleagues wanted to see whether incorporating gold nanoparticles into contact lens material
instead of dye could improve red-green contrast safely and
effectively.
To make the contact lenses, the researchers evenly mixed
gold nanoparticles into a hydrogel polymer, producing
rose-tinted gels that filtered light within 520-580 nm, the
wavelengths where red and green overlap. The most effective contact lenses were those with 40-nm-wide gold
nanoparticles, because in tests, these particles did not
clump or filter more color than necessary. In addition,
these lenses had water-retention properties similar to those
of commercial ones and were not toxic to cells growing in
petri dishes in the lab. Finally, the researchers directly compared their new material to two commercially available
pairs of tinted glasses, and their previously developed hotpink dyed contact lens.
The gold nanocomposite lenses were more selective in
the wavelengths they blocked than the glasses. The new
lenses matched the wavelength range of the dyed contact
lenses, suggesting the gold nanocomposite ones would be
suitable for people with red-green color issues without the
potential safety concerns. The researchers say that the next
step is to conduct clinical trials with human patients to
assess comfort.
For more information, visit http://www.acs.org.
Medical Design Briefs, May 2021

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Medical Design Briefs - May 2021

Table of Contents for the Digital Edition of Medical Design Briefs - May 2021

Medical Design Briefs - May 2021 - Intro
Medical Design Briefs - May 2021 - Cov4
Medical Design Briefs - May 2021 - Cov1
Medical Design Briefs - May 2021 - Cov2
Medical Design Briefs - May 2021 - 1
Medical Design Briefs - May 2021 - 2
Medical Design Briefs - May 2021 - 3
Medical Design Briefs - May 2021 - 4
Medical Design Briefs - May 2021 - 5
Medical Design Briefs - May 2021 - 6
Medical Design Briefs - May 2021 - 7
Medical Design Briefs - May 2021 - 8
Medical Design Briefs - May 2021 - 9
Medical Design Briefs - May 2021 - 10
Medical Design Briefs - May 2021 - 11
Medical Design Briefs - May 2021 - 12
Medical Design Briefs - May 2021 - 13
Medical Design Briefs - May 2021 - 14
Medical Design Briefs - May 2021 - 15
Medical Design Briefs - May 2021 - 16
Medical Design Briefs - May 2021 - 17
Medical Design Briefs - May 2021 - 18
Medical Design Briefs - May 2021 - 19
Medical Design Briefs - May 2021 - 20
Medical Design Briefs - May 2021 - 21
Medical Design Briefs - May 2021 - 22
Medical Design Briefs - May 2021 - 23
Medical Design Briefs - May 2021 - 24
Medical Design Briefs - May 2021 - 25
Medical Design Briefs - May 2021 - 26
Medical Design Briefs - May 2021 - 27
Medical Design Briefs - May 2021 - 28
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Medical Design Briefs - May 2021 - 31
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Medical Design Briefs - May 2021 - 33
Medical Design Briefs - May 2021 - 34
Medical Design Briefs - May 2021 - 35
Medical Design Briefs - May 2021 - 36
Medical Design Briefs - May 2021 - 37
Medical Design Briefs - May 2021 - 38
Medical Design Briefs - May 2021 - 39
Medical Design Briefs - May 2021 - 40
Medical Design Briefs - May 2021 - Cov3
Medical Design Briefs - May 2021 - Cov4
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