Medical Design Briefs - July 2021 - 25

To pre-amplifier
campus and cerebral cortex is twosided:
sometimes the cortex initiates
communication, other times it's the
hippocampus. This is an important first
clue for understanding inter-region
communication in the brain, the
researchers says.
" The hippocampal-cortical interaction
is important in memory consolidation
and retrieval, " says Ren. " The twosided
communication we reported here
is different from the conventional
notion that the cortex passively receives
the information from the hippocampus.
Instead, the cortex is actively
involved in encoding information into
the brain and may play an instructive
role during memory consolidation and
retrieval. "
" We can now begin new studies to
unlock how processes like learning
and memory happen, "
says Kuzum.
" For example, when the brain acquires
new information, how does the hipWe
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tive processes, such as learning and
memory formation, occur in the brain.
Such processes involve communication
between the hippocampus and cerebral
cortex.
But how exactly does this communication
happen? And which brain
region initiates this communication:
the hippocampus or the cerebral cortex?
These types of questions have
been left unanswered because it is very
difficult to study these two brain
regions simultaneously, says Kuzum.
" We were interested in investigating
the nature of cortical-hippocampal
interactions, so we built a technology to
explore this neuroscience problem, "
she says.
The researchers used their probe to
monitor the activity of the hippocampus
and the cerebral cortex in transgenic
mice. Specifically, they monitored activity
before, during and after oscillations
that occur in the hippocampus called
sharp-wave ripples.
Their
experiments
revealed
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Medical Design Briefs, July 2021
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Medical Design Briefs - July 2021

Table of Contents for the Digital Edition of Medical Design Briefs - July 2021

Medical Design Briefs - July 2021 - Intro
Medical Design Briefs - July 2021 - Cov4
Medical Design Briefs - July 2021 - Cov1
Medical Design Briefs - July 2021 - Cov2
Medical Design Briefs - July 2021 - 1
Medical Design Briefs - July 2021 - 2
Medical Design Briefs - July 2021 - 3
Medical Design Briefs - July 2021 - 4
Medical Design Briefs - July 2021 - 5
Medical Design Briefs - July 2021 - 6
Medical Design Briefs - July 2021 - 7
Medical Design Briefs - July 2021 - 8
Medical Design Briefs - July 2021 - 9
Medical Design Briefs - July 2021 - 10
Medical Design Briefs - July 2021 - 11
Medical Design Briefs - July 2021 - 12
Medical Design Briefs - July 2021 - 13
Medical Design Briefs - July 2021 - 14
Medical Design Briefs - July 2021 - 15
Medical Design Briefs - July 2021 - 16
Medical Design Briefs - July 2021 - 17
Medical Design Briefs - July 2021 - 18
Medical Design Briefs - July 2021 - 19
Medical Design Briefs - July 2021 - 20
Medical Design Briefs - July 2021 - 21
Medical Design Briefs - July 2021 - 22
Medical Design Briefs - July 2021 - 23
Medical Design Briefs - July 2021 - 24
Medical Design Briefs - July 2021 - 25
Medical Design Briefs - July 2021 - 26
Medical Design Briefs - July 2021 - 27
Medical Design Briefs - July 2021 - 28
Medical Design Briefs - July 2021 - 29
Medical Design Briefs - July 2021 - 30
Medical Design Briefs - July 2021 - 31
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Medical Design Briefs - July 2021 - 35
Medical Design Briefs - July 2021 - 36
Medical Design Briefs - July 2021 - 37
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Medical Design Briefs - July 2021 - 39
Medical Design Briefs - July 2021 - 40
Medical Design Briefs - July 2021 - Cov3
Medical Design Briefs - July 2021 - Cov4a
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