Tech Briefs Magazine - May 2021 - 47

AUTOMOTIVE / TRUCK & OFF HIGHWAY / AEROSPACE & DEFENSE

Tiny 3D-Printed Bricks Enable
Bone and Soft Tissue Repair
Flea-sized, hollow blocks can be filled with
materials that improve healing.
Oregon Health & Science University, Portland

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T

iny, 3D-printed bricks have been designed to heal broken
bones and could one day lead to lab-made organs for human
transplant. Inspired by LEGO® blocks, the small, hollow bricks
serve as scaffolding onto which both hard and soft tissue can
regrow better than today's standard regeneration methods.
Each brick is 1.5 mm3, or roughly the size of a small flea. The
scaffolding can be stacked together like LEGOs and placed in
thousands of different configurations to match the complexity
and size of almost any situation.
Orthopedic surgeons typically repair more complex bone
fractures by implanting metal rods or plates to stabilize the
bone and then inserting biocompatible scaffolding materials
packed with powders or pastes that promote healing. A unique
advantage of the new scaffolding system is that its hollow blocks
can be filled with small amounts of gel containing various
growth factors that are precisely placed closest to where they are
needed. Growth-factor-filled blocks placed near repaired rat
bones led to about three times more blood vessel growth than
conventional scaffolding material.
The 3D-printed microcage technology improves healing by
stimulating the right type of cells to grow in the right place at the
right time. Different growth factors can be placed inside each
block, enabling more precise and quicker repair tissue.
The small devices are modular and can be assembled to fit into
almost any space. When piecing together block segments containing four layers of four bricks by four bricks, the researchers estimate more than 29,000 different configurations can be created.

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Tiny, 3D-printed bricks can be assembled like LEGO blocks to help repair
broken bones and soft tissue. (OHSU)

Tech Briefs, May 2021

Free Info at http://info.hotims.com/79413-736

Cov

ToC

47

http://WWW.IPCOL.COM http://info.hotims.com/79413-735 http://info.hotims.com/79413-736 http://www.abpi.net/ntbpdfclicks/l.php?202105TBNAV

Tech Briefs Magazine - May 2021

Table of Contents for the Digital Edition of Tech Briefs Magazine - May 2021

Tech Briefs Magazine - May 2021 - Intro
Tech Briefs Magazine - May 2021 - Sponsor
Tech Briefs Magazine - May 2021 - Cov1
Tech Briefs Magazine - May 2021 - Cov2
Tech Briefs Magazine - May 2021 - 1
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Tech Briefs Magazine - May 2021 - 3
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Tech Briefs Magazine - May 2021 - 46
Tech Briefs Magazine - May 2021 - 47
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Tech Briefs Magazine - May 2021 - Cov3
Tech Briefs Magazine - May 2021 - Cov4
Tech Briefs Magazine - May 2021 - PIT-Cov1
Tech Briefs Magazine - May 2021 - PIT-Cov2
Tech Briefs Magazine - May 2021 - PIT-1
Tech Briefs Magazine - May 2021 - PIT-2
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Tech Briefs Magazine - May 2021 - PIT-28
Tech Briefs Magazine - May 2021 - PIT-Cov3
Tech Briefs Magazine - May 2021 - PIT-Cov4
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