Medical Design Briefs - June 2022 - 4

The Power of the Smartwatch:
Bridging Consumer and Medtech
Innovation
S
martwatches: These ubiquitous wearables
have become a powerful tool
for diagnosis and health monitoring in
areas ranging from cardiology to diabetes
to the effects of a COVID-19 vaccine.
Glucose monitoring is essential for
the millions of people with diabetes.
PKvitality, a French company specializing
in biowearable health and sports,
recently presented the results of firstin-human
trial of its K'Watch Glucose,
a continuous glucose monitoring device
in the form of a smartwatch. According
to the company, the system
measures glucose levels by analyzing
interstitial fluid (ISF) through micropoints.
The system enables a painless
and nonstigmatizing experience, solving
the adhesive issue in a design-tocost
architecture.
The trial showed great user experience
and tracking. It took place at AMCR
Institute, a clinical research center focused
on diabetes and obesity with
worldwide renowned medical device expertise
in the metabolic area.
" PKvitality is a unique blend of consumer
electronic and medtech expertise,
bringing the best of both worlds:
appealing product, ease of use at the service
of the diabetes patients, " says Luc
PiƩrart, CEO of PKvitality.
Similarly, a recent study from Scripps
Research demonstrates how data from
wearable sensors, such as smartwatches
and fitness bands, can also track a person's
physiological response to the
COVID-19 vaccination. For the Scripps
study, researchers drew their data from
a larger project called Digital Engagement
and Tracking for Early Control
and Treatment (DETECT), which was
launched in March 2020 in response to
the emergence and rapid spread of
SARS-CoV-2, the virus that causes
COVID-19. DETECT is a mobile-app
research platform that allows participants
to share physiological and behavioral
data gathered through a fitness
band or smartwatch, as well as manually
entered symptoms, test results, and
vaccination status.
To determine whether consumer wearables
could unearth digital biomarkers of
vaccine-induced immune response, the
Scripps scientists analyzed DETECT sen4
Cov
MDB
From the Editor 0622_1.indd 4
The K'Watch measures glucose levels
by analyzing interstitial fluid (ISF) through
micropoints. (Credit: PKvitality)
sor data from two weeks before and after
each vaccination dose. They compared
post-vaccination changes to the participants'
resting heart rate, sleep, and activity
levels to their baselines.
" DETECT really shows the power of
wearable sensor data in furthering our
understanding of multiple facets of
COVID-19, " says Giorgio Quer, PhD, director
of Artificial Intelligence at the
Scripps Research Translational Institute.
" We hope to continue to expand this research
by growing our study cohort further,
which will allow us to delve into
important questions regarding breakthrough
infections and other areas that
are currently poorly understood. "
The study analyzed sensor data on
sleep, activity, and heart rate from over
5,600 individuals. Among the findings,
the team showed that the average resting
heart rate of participants significantly
increased the day following vaccination.
The effect appeared to be
stronger after the second dose of the
Moderna vaccine, compared to the Pfizer-BioNTech
vaccine, and more pronounced
in younger individuals.
The analysis showed that the resting
heart rate of study participants peaked
two days post-vaccination and returned
to normal four days after the first dose
and six days after the second. In addition
to increases in resting heart rate
being higher after the second dose of
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5/26/22 1:29 PM
the Moderna versus the PfizerBioNTech
vaccine, the study
suggests that prior COVID-19
infection was linked with a
significantly higher resting
heart rate increase after the
first vaccine dose relative to
those without prior infection.
This increase is consistent
with an expected
greater immune response
for these individuals.
The findings also show
that women experienced
greater changes than men
in resting heart rate in the
five days following vaccination
after the first dose, and that individuals
under the age of 40 had higher
changes in resting heart rate than older
individuals, but only after the second
dose. Activity and sleep patterns appeared
to be minimally affected by the
first dose, but a significant decrease in
activity and an increase in sleep relative
to baseline were observed immediately
after the second vaccine dose.
Another study, which involved more
than 2.8 million participants, is the largest
study to date to demonstrate how
wearable consumer technologies can be
used to screen for heart problems during
everyday activities. Researchers screened
a subset of participants for obstructive
sleep apnea and found that people
flagged for possible sleep apnea were 1.5
times more likely to have AFib than
those who were not. According to the
study, this finding suggests that tools suitable
for detecting the two conditions can
work synergistically to further enhance
health monitoring.
" Digital technologies make it possible
to increase general awareness about
AFib and its risk factors as well as to improve
prevention of AFib and its complications, "
says Yutao Guo, MD, professor
of internal medicine at Chinese PLA
Medical School and Chinese PLA General
Hospital in Beijing and the study's
lead author. " With the global surge of
wearable technology for AFib screening,
especially in the challenging setting of
the COVID-19 pandemic, the present
study provides a possible solution to help
people identify possible signs of AFib
and get diagnosed and treated earlier. "
Sherrie Trigg
Editor and Director of Medical Content
Medical Design Briefs, June 2022
http://www.medicaldesignbriefs.com

Medical Design Briefs - June 2022

Table of Contents for the Digital Edition of Medical Design Briefs - June 2022

Medical Design Briefs - June 2022 - Intro
Medical Design Briefs - June 2022 - Cov4
Medical Design Briefs - June 2022 - Cov1a
Medical Design Briefs - June 2022 - Cov1b
Medical Design Briefs - June 2022 - Cov1
Medical Design Briefs - June 2022 - Cov2
Medical Design Briefs - June 2022 - 1
Medical Design Briefs - June 2022 - 2
Medical Design Briefs - June 2022 - 3
Medical Design Briefs - June 2022 - 4
Medical Design Briefs - June 2022 - 5
Medical Design Briefs - June 2022 - 6
Medical Design Briefs - June 2022 - 7
Medical Design Briefs - June 2022 - 8
Medical Design Briefs - June 2022 - 9
Medical Design Briefs - June 2022 - 10
Medical Design Briefs - June 2022 - 11
Medical Design Briefs - June 2022 - 12
Medical Design Briefs - June 2022 - 13
Medical Design Briefs - June 2022 - 14
Medical Design Briefs - June 2022 - 15
Medical Design Briefs - June 2022 - 16
Medical Design Briefs - June 2022 - 17
Medical Design Briefs - June 2022 - 18
Medical Design Briefs - June 2022 - 19
Medical Design Briefs - June 2022 - 20
Medical Design Briefs - June 2022 - 21
Medical Design Briefs - June 2022 - 22
Medical Design Briefs - June 2022 - 23
Medical Design Briefs - June 2022 - 24
Medical Design Briefs - June 2022 - 25
Medical Design Briefs - June 2022 - 26
Medical Design Briefs - June 2022 - 27
Medical Design Briefs - June 2022 - 28
Medical Design Briefs - June 2022 - 29
Medical Design Briefs - June 2022 - 30
Medical Design Briefs - June 2022 - 31
Medical Design Briefs - June 2022 - 32
Medical Design Briefs - June 2022 - 33
Medical Design Briefs - June 2022 - 34
Medical Design Briefs - June 2022 - 35
Medical Design Briefs - June 2022 - 36
Medical Design Briefs - June 2022 - 37
Medical Design Briefs - June 2022 - 38
Medical Design Briefs - June 2022 - 39
Medical Design Briefs - June 2022 - 40
Medical Design Briefs - June 2022 - 41
Medical Design Briefs - June 2022 - 42
Medical Design Briefs - June 2022 - 43
Medical Design Briefs - June 2022 - 44
Medical Design Briefs - June 2022 - 45
Medical Design Briefs - June 2022 - 46
Medical Design Briefs - June 2022 - 47
Medical Design Briefs - June 2022 - 48
Medical Design Briefs - June 2022 - 49
Medical Design Briefs - June 2022 - 50
Medical Design Briefs - June 2022 - 51
Medical Design Briefs - June 2022 - 52
Medical Design Briefs - June 2022 - 53
Medical Design Briefs - June 2022 - 54
Medical Design Briefs - June 2022 - 55
Medical Design Briefs - June 2022 - 56
Medical Design Briefs - June 2022 - 57
Medical Design Briefs - June 2022 - 58
Medical Design Briefs - June 2022 - 59
Medical Design Briefs - June 2022 - 60
Medical Design Briefs - June 2022 - 61
Medical Design Briefs - June 2022 - 62
Medical Design Briefs - June 2022 - 63
Medical Design Briefs - June 2022 - 64
Medical Design Briefs - June 2022 - 65
Medical Design Briefs - June 2022 - 66
Medical Design Briefs - June 2022 - 67
Medical Design Briefs - June 2022 - 68
Medical Design Briefs - June 2022 - 69
Medical Design Briefs - June 2022 - 70
Medical Design Briefs - June 2022 - 71
Medical Design Briefs - June 2022 - 72
Medical Design Briefs - June 2022 - 73
Medical Design Briefs - June 2022 - 74
Medical Design Briefs - June 2022 - 75
Medical Design Briefs - June 2022 - 76
Medical Design Briefs - June 2022 - 77
Medical Design Briefs - June 2022 - 78
Medical Design Briefs - June 2022 - 79
Medical Design Briefs - June 2022 - 80
Medical Design Briefs - June 2022 - 81
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Medical Design Briefs - June 2022 - 83
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Medical Design Briefs - June 2022 - 85
Medical Design Briefs - June 2022 - 86
Medical Design Briefs - June 2022 - 87
Medical Design Briefs - June 2022 - 88
Medical Design Briefs - June 2022 - Cov3
Medical Design Briefs - June 2022 - Cov4a
https://www.nxtbook.com/smg/techbriefs/22MDB09
https://www.nxtbook.com/smg/techbriefs/22MDB08
https://www.nxtbook.com/smg/techbriefs/22MDB07
https://www.nxtbook.com/smg/techbriefs/22MDB06
https://www.nxtbook.com/smg/techbriefs/22MDB04
https://www.nxtbook.com/smg/techbriefs/techleaders21
https://www.nxtbook.com/smg/techbriefs/22MDB03
https://www.nxtbook.com/smg/techbriefs/22MDB02
https://www.nxtbook.com/smg/techbriefs/22MDB01
https://www.nxtbook.com/smg/techbriefs/21MDB12
https://www.nxtbook.com/smg/techbriefs/21MDB11
https://www.nxtbook.com/smg/techbriefs/21MDB10
https://www.nxtbook.com/smg/techbriefs/21MDB09
https://www.nxtbook.com/smg/techbriefs/21MDB08
https://www.nxtbook.com/smg/techbriefs/21MDB07
https://www.nxtbook.com/smg/techbriefs/21MDB06
https://www.nxtbook.com/smg/techbriefs/21MDB05
https://www.nxtbook.com/smg/techbriefs/21MDB04
https://www.nxtbook.com/smg/techbriefs/21MDB02
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