Medical Design Briefs - February 2024 - 54

Design Briefs
Peristaltic
Pump
Flow stability and precision
Response time
Ultrasmooth flow
Low
Low
Low
Direct handling of media (cross contamination) Yes
Size, weight, noise
Gas injection
Injection of nano-volume sample
Sample agitation
Sample temperature control
Dynamic flow range
Fluid recirculation
Syringe
Pump
Pressure
Driven Flow
Medium Excellent
Low
Excellent
Medium Excellent
Yes
No
Medium Poor
No
No
Poor
Possible
Possible
Good
Yes
Good
Not
Possible
Not
Possible
Poor
No
Excellent*
Yes
Medium**
Possible
Possible
Excellent
Yes***
*with Lee Ventis disc pump **limited only by flow sensor accuracy ***valves needed
Table 1. The performance of the disc pump compared with traditional technologies used in pressure driven flow.
and connected to the cuff by a hose. This
hose can kink and interfere with measurements,
so removing it is an advantage.
The disc pump is small and lightweight
enough to be directly integrated
into arm-worn modules, eliminating the
need for a hose.
Pressure Driven Flow/
Air-Over Liquid
Pressure
driven
flow
(PDF),
also
known as air over liquid, is a liquid transport
mechanism in which air pressure is
used to move liquid through a system.
This approach is used in many applications
from point-of-care diagnostics to
organ-on-a-chip and drug-delivery systems.
It addresses several drawbacks of
traditional liquid pumping, such as the
risk of cross contamination, because the
pump never comes into contact with the
liquid being handled.
The disc pump is an excellent pressure
source for PDF. Operating in a closedloop
system, its high-precision pressure
control provides exceptional control
over liquid flow. The pulsation-free output
and rapid response speed enables
liquids to be moved exactly as intended,
whether in smooth laminar flow streams
for microfluidic research, or oscillating
profiles intended to mimic blood flow in
the body (see Figure 2).
Using gas pressure to move liquids
provides many other benefits over
traditional technologies, such as peristaltic
pumps and syringe pumps, as detailed
in Table 1. As the disc pump can
generate both positive and negative pressure,
it can also be used for applications
like pipetting and time-metered dosing,
where the disc pump's ability to accurately
control pressure translates across into
accurate liquid control. For example, in
time- metered dosing, the head pressure
above a body of liquid is accurately controlled,
and the dispensed volume is then
governed by a fast-acting valve.
Testing in A Project:
Disc Pump Development Kit
A development kit includes the electronics
and accessories needed to start
developing a medical device or fluid
handling system. The development kit
can drive multiple disc pumps, smart
pump modules, and solenoid valves.
These products are provided individually,
enabling designers to tailor the kit
with the solenoid valve and pump model
that best fits specific requirements.
This article was written by Emma Wilson,
Marketing Manager for Lee Ventus,
Cambridge, UK. For more information,
contact enquiries@theleeco.uk or visit
www.theleeco.com/DevKit. The kit
will be demonstrated in booth #3219 at
MD&M West.
The Use of Parylene-Coated Mandrels in the
Balloon Catheter Manufacturing Process
Parylenes withstand typical temperatures used in balloon attachment.
By Carla Gillespie, Specialty Coating Systems
he process of manufacturing highquality
and reliable balloon catheters
is critical to a number of advanced
medical treatments for patients including
balloon angioplasty, stent and drug delivery,
transcatheter aortic valve implantation,
atherectomy, renal denervation, and
laser balloon angioplasty. These minimally
invasive procedures have vastly improved
54
T
quality of life, increased patient safety, decreased
recovery times, and lowered treatment
costs for patients around the globe.
Balloon catheters are polymer balloons
that are attached to catheters at points on
each end of the balloon. The bond made
between the balloon and catheter requires
heat sealing via direct thermal
compression, RF welding or laser processwww.medicaldesignbriefs.com
ing.
In each case, the process requires a
hard surface inside the catheter/balloon
pair to press against in order to optimize
the bond, enabling it to contain the inflation
pressures required during use. A precisely
sized wire forming-mandrel is inserted
through the catheter and the
overlapping balloon in order to stage the
assembly for sealing. After the sealing
Medical Design Briefs, February 2024
http://www.theleeco.com/DevKit http://www.medicaldesignbriefs.com

Medical Design Briefs - February 2024

Table of Contents for the Digital Edition of Medical Design Briefs - February 2024

Medical Design Briefs - February 2024 - Cover Flap
Medical Design Briefs - February 2024 - Cover Flap1A
Medical Design Briefs - February 2024 - Cover1
Medical Design Briefs - February 2024 - Cover2
Medical Design Briefs - February 2024 - 1
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Medical Design Briefs - February 2024 - Cover3
Medical Design Briefs - February 2024 - Cover4
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