HIV Specialist - June 2021 - 8

INFORMATION FOR HIV CARE PROVIDERS
IN
THE
NEWS
England on Track to Achieve Elimination of
HIV Transmission by 2030
Model shows sharp decrease in HIV incidence
THE ANNUAL NUMBER of new HIV infections
among men who have sex with men (MSM) in
England is likely to have fallen dramatically,
from 2,770 in 2013 to 854 in 2018, showing
elimination of HIV transmission by 2030
to be within reach-suggests work by
researchers from the MRC Biostatistics Unit
at the University of Cambridge and Public Health
England, published in The Lancet HIV.
To manage the HIV epidemic among men who have
sex with men (MSM) in England, enhanced testing and
earlier treatment strategies were scaled-up between 2011
and 2015 and supplemented from 2015 by pre-exposure
prophylaxis (PrEP). The researchers examined the effect of
these interventions on the number of new infections and
investigated whether the United Nations (UN) targets for
HIV control and elimination of HIV transmission by 2030
might be within reach among MSM in England.
A complexity in this assessment is that HIV infections
are not observed. Routine surveillance collects data on
new HIV diagnoses, but trends in new diagnoses alone
can be misleading as they can represent infections that
occurred many years previously and depend on the
testing behaviour of infected individuals.
To estimate new HIV infections among adult MSM (age
15 years and above) over a 10-year period between 2009
and 2018, the researchers used a novel statistical model
that used data on HIV and AIDS diagnoses routinely
collected via the national HIV and AIDS Reporting System
in England, and knowledge on the progression of HIV.
Estimated trends in new infections were then extrapolated
to understand the likelihood of achieving the UN
elimination target defined as less than one newly acquired
infection per 10,000 MSM per year, by 2030.
The peak in the number of new HIV infections in
MSM in England is estimated to have occurred between
2012 and 2013, followed by a steep decrease from 2,770
new infections in 2013 to 1,740 in 2015, and a further
steadier decrease from 2016, down to 854. The decline
was consistent across all age groups but was particularly
8 JUNE 2021 HIVSPECIALIST WWW.AAHIVM.ORG
marked in MSM aged 25-34 years, and slowest in those
aged 45 years or older. Importantly, this decrease began
before the widespread roll-out of PrEP in 2016, indicating
the success of testing and treatment as infection
prevention measures among MSM in England.
Through extrapolation, the researchers calculated a
40% likelihood of England reaching the UN elimination
target by 2030 and identified relevant age-specific
targeting of further prevention efforts (i.e., to MSM aged
≥45 years) to increase this likelihood.
Senior author, Professor Daniela De Angelis, Deputy
Director of the MRC Biostatistics Unit, University of
Cambridge, said: " This is very good news and suggests that
prevention measures adopted in England from 2011 have been
effective. With the rollout of PrEP, England looks on course
to meet the goal of zero transmissions by 2030. Our study
also shows the value of regular estimation of HIV incidence
to recognise and respond appropriately to changes in the
current downward trend. The challenge now is to achieve
these reductions in all groups at risk for HIV acquisition. "
Valerie Delpech, Head of National HIV Surveillance
at Public Health England, said: " We have made good
progress towards ending HIV transmission by 2030
in England. Frequent HIV testing and the use of PrEP
amongst people most at risk of HIV, together with prompt
treatment among those diagnosed, are key to ending HIV
transmission by 2030.
" You can benefit from life-saving HIV treatments if you
are diagnosed with HIV and it also means you cannot pass
the virus on.
" HIV and STI tests are still available through sexual
health clinics during the COVID pandemic. Many clinics
offer online testing throughout the year-people can order
tests on clinic websites, take them in the privacy of their
own home, return by post and receive results via text,
phone call or post. "
This research is funded by the UK Medical Research
Council, UK National Institute of Health Research Health
Protection Unit in Behavioural Science and Evaluation, and
Public Health England.
STOCK.ADOBE.COM/ SOMARTIN
http://WWW.AAHIVM.ORG http://STOCK.ADOBE.COM/

HIV Specialist - June 2021

Table of Contents for the Digital Edition of HIV Specialist - June 2021

HIV Specialist - June 2021 - Cover1
HIV Specialist - June 2021 - Cover2
HIV Specialist - June 2021 - 1
HIV Specialist - June 2021 - 2
HIV Specialist - June 2021 - 3
HIV Specialist - June 2021 - 4
HIV Specialist - June 2021 - 5
HIV Specialist - June 2021 - 6
HIV Specialist - June 2021 - 7
HIV Specialist - June 2021 - 8
HIV Specialist - June 2021 - 9
HIV Specialist - June 2021 - 10
HIV Specialist - June 2021 - 11
HIV Specialist - June 2021 - 12
HIV Specialist - June 2021 - 13
HIV Specialist - June 2021 - 14
HIV Specialist - June 2021 - 15
HIV Specialist - June 2021 - 16
HIV Specialist - June 2021 - 17
HIV Specialist - June 2021 - 18
HIV Specialist - June 2021 - 19
HIV Specialist - June 2021 - 20
HIV Specialist - June 2021 - 21
HIV Specialist - June 2021 - 22
HIV Specialist - June 2021 - 23
HIV Specialist - June 2021 - 24
HIV Specialist - June 2021 - 25
HIV Specialist - June 2021 - 26
HIV Specialist - June 2021 - 27
HIV Specialist - June 2021 - 28
HIV Specialist - June 2021 - 29
HIV Specialist - June 2021 - 30
HIV Specialist - June 2021 - 31
HIV Specialist - June 2021 - 32
HIV Specialist - June 2021 - 33
HIV Specialist - June 2021 - 34
HIV Specialist - June 2021 - 35
HIV Specialist - June 2021 - 36
HIV Specialist - June 2021 - 37
HIV Specialist - June 2021 - 38
HIV Specialist - June 2021 - 39
HIV Specialist - June 2021 - 40
HIV Specialist - June 2021 - 41
HIV Specialist - June 2021 - 42
HIV Specialist - June 2021 - 43
HIV Specialist - June 2021 - 44
HIV Specialist - June 2021 - 45
HIV Specialist - June 2021 - 46
HIV Specialist - June 2021 - 47
HIV Specialist - June 2021 - 48
HIV Specialist - June 2021 - 49
HIV Specialist - June 2021 - 50
HIV Specialist - June 2021 - 51
HIV Specialist - June 2021 - 52
HIV Specialist - June 2021 - Cover3
HIV Specialist - June 2021 - Cover4
https://www.nxtbook.com/ygsreprints/AAHIVM/hiv-specialist-june-2021
https://www.nxtbook.com/ygsreprints/AAHIVM/hiv-specialist-march-2021
https://www.nxtbook.com/ygsreprints/AAHIVM/G121337_AAHIV_122020
https://www.nxtbook.com/ygsreprints/AAHIVM/G119632_AAHIV_092020
https://www.nxtbook.com/ygsreprints/AAHIVM/G118334_AAHIV_062020
https://www.nxtbook.com/ygsreprints/AAHIVM/G116663_AAHIVM_032020
https://www.nxtbookmedia.com