Viking Magazine - December 2015 - 12

FOR ADULTS WITH DUPUYTREN'S
CONTRACTURE WHEN A " CORD " CAN BE FELT
YOU MAY HAVE MORE OPTIONS THAN YOU THINK
XIAFLEX®
FOR INJECTION
ASK YOUR DOCTOR IF SOMETHING NONSURGICAL CAN BE DONE NOW
Dupuytren's contracture is a disorder of the hand that can worsen over time. XIAFLEX®
is the only
FDA-approved therapy that is administered during an in-offi ce nonsurgical procedure to treat
Dupuytren's contracture where a " rope-like " cord can be felt. A hand specialist trained to inject XIAFLEX®
performs the procedure, and no general anesthesia is required for administration.
Studies show that prescription XIAFLEX ®
, along with a fi nger-extension procedure, may help straighten or
nearly straighten the affected fi nger and improve range of motion after up to 3 injections. These results have
been shown in contractures ranging from less severe to more severe.
In two clinical studies, 64% and 44% of patients receiving XIAFLEX®
placebo) had a straight or nearly straight fi nger after up to 3 XIAFLEX®
?
(versus 7% and 5% of patients receiving
injection procedures.
Since February 2010, approximately 60,000 people have had their Dupuytren's contracture treated with XIAFLEX®
WHAT IS XIAFLEX®
XIAFLEX®
when a " cord " can be felt. It is not known if XIAFLEX®
under the age of 18.
is a prescription medicine used to treat adults with Dupuytren's contracture
is safe and effective in children
IMPORTANT SAFETY INFORMATION for XIAFLEX®
Do not receive XIAFLEX®
of the ingredients in XIAFLEX®
XIAFLEX®
if you are allergic to collagenase clostridium histolyticum or any
, or to any other collagenase product.
can cause serious side effects including tendon rupture (break) or ligament damage
which could require surgery, nerve injury or other serious injury of the hand, allergic reaction or
hypersensitivity reactions, including anaphylaxis and increased chance of bleeding.
Call your healthcare provider right away if you have trouble bending your injected fi nger
after the swelling goes down, problems using your treated hand, pain, tingling, numbness,
increased pain, or tears in the skin (laceration) in your treated hand.
Call your healthcare provider right away if you get hives, swollen face, breathing trouble, chest
pain, low blood pressure, dizziness or fainting. It's important to tell your doctor if you have had a
previous allergic reaction to XIAFLEX®
.
Bleeding or bruising at the injection site is common in people who receive XIAFLEX®
your doctor if you have a bleeding problem or use a blood thinner. XIAFLEX®
. It's important to tell
may not be right for you.
Other common side effects include swelling, pain or tenderness at injection site or hand, swelling of glands
in the elbow or armpit, itching, breaks or redness or warmth in the skin, and pain in the armpit.
Tell your doctor if you have any other medical conditions and about all the medications you take. XIAFLEX®
should be injected into the cord by a healthcare provider who is experienced in injection procedures of
the hand and treating people with Dupuytren's contracture.
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Please see the Medication Guide on the following page.
Find a XIAFLEX®
-experienced
hand specialist near you.
Use the Physician Locator tool
at XIAFLEX.com/viking.
FOR MORE INFORMATION, CALL 1-877-XIAFLEX.
Rx Only
XIAFLEX® is a registered trademark of Endo International plc or one of its affi liates.
© 2015 Endo Pharmaceuticals Inc. All rights reserved. Malvern, PA 19355
XD-03881f/July 2015 www.xiafl ex.com 1-800-462-ENDO (3636)
.
Watch a video
about one person's
treatment experience,
and fi nd more information
at XIAFLEX.com. Then, talk
with your doctor to see
if XIAFLEX®
may be
right for you.

http://www.XIAFLEX.com http://www.fda.gov/medwatch http://www.XIAFLEX.com/viking http://www.xiafl http://www.ex.com

Viking Magazine - December 2015

Table of Contents for the Digital Edition of Viking Magazine - December 2015