IntelliCyt eBook - October 2017 - 15

Development & Optimization: The Dynamic Duo of Biomanufacturing * Analytical Power Tools Open Upstream Bioprocessing Bottlenecks

in cell and reagent loss. Wide dynamic range eliminates laborintensive dilution of unknown samples. This streamlined design
means a Cy-Clone assay set-up takes about an hour. Plus, there is no
tedious preparation for data acquisition. A memory stick included
in the kit has a pre-configured template complete with gates. Data
acquisition begins immediately on the iQue Screener PLUS and takes
20 minutes for a 384-well plate.

ForeCyt - Optimize, Analyze, Visualize, Realize...Faster!
ForeCyt Software-produces actionable IgG clone data by
generating cell-line plate heat maps, histograms, plots, dose
response curves, and profile maps. A multi-plate analysis feature in
the ForeCyt Software, called Panorama, generates an analytical "big
picture" that automatically compares, identifies, and ranks the IgG
clones at the screening campaign level (Figure 3) across multiple
plates of an experiment, as well as multiple plates in an experiment
over several days. In addition, criteria threshold slider bars adjust
data on the fly for real-time "what if" analyses of plate data with
the click of a mouse.
Panorama provides a capability to instantly dial-in an optimized
set of IgG clones to move forward, eliminating the weeks or months
of loading, reloading, and recalculating data required by legacy
platforms.
15

| GENengnews.com

Figure 3. Cross-Plate Data Analysis Identifying Best Productive IgG Clones in
a Screening Campaign

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IntelliCyt eBook - October 2017

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