Medical Design Briefs - June 2022 - 12

Designing
Lenses
for Near-Infrared and
Fluorescence Endoscopy
Lenses for near-infrared and
fl uorescence endoscopy.
F
12
Cov
MDB Tamron Feature 0622-CC_1.indd 12
luorescence endoscopy is becoming
increasingly important
in many medical diagnostic tests.
Based on the molecular absorption
of light, this technique works
by revealing tissue abnormalities that are
hidden from view under normal white
light. Already, fl uorescence endoscopy
can improve the endoscopic detection of
nonvisible malignant lesions or tumors,
for example.
Sensitizers, chemicals that can cause
allergic reactions, accumulate in these
lesions. These sensitizers induce tissue
fl uorescence in response to certain wavelengths
of light. In the fi eld of gastroenterology,
this ability to reveal and visualize
lesions holds promise for the early
detection of dysplasia and cancers. Similarly,
near-infrared (NIR) fl uorescence
rigid endoscopic imaging systems are
emerging as a critical tool in some brain
surgeries.
Fluorescence endoscopy, which
is gaining ground in these and other
medical applications compared
to traditional white light endoscopic
techniques, places some unique
requirements on optical lenses (see
the sidebar, " Current NIR Fluorescence
Imaging Applications " ). For
example, a lens with the right combination
of high-resolution, antireflective
coatings and minimal focus shift
can enable better fluorescence imaging
across the visible and NIR range,
which includes wavelengths between
400 and 850 nm.
This article discusses various lens design
considerations, including optical
fi lters and antirefl ective coatings, that
can further optimize the performance
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ToC
5/25/22 2:47 PM
of NIR fluorescence endoscopy in
medical and life science applications.
Antirefractive Lens-Coating
Technologies
Recent advancements in coating and
thin-fi lter optical technologies are resulting
in more applications in the medical
and life science industries, including
optimizing NIR fl uorescence endoscopic
techniques. One such advancement,
called the extended bandwidth and angular
dependency (eBAND) lens coating,
deploys a nanostructured layer with an
ultra-low refractive index, the dimensions
of which are smaller than the wavelengths
of visible light.
This nanostructured layer, coupled
with sophisticated multilayer coatings
underneath, yields signifi cant antirefl ection
properties. By suppressing tangenMedical
Design Briefs, June 2022
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Medical Design Briefs - June 2022

Table of Contents for the Digital Edition of Medical Design Briefs - June 2022

Medical Design Briefs - June 2022 - Intro
Medical Design Briefs - June 2022 - Cov4
Medical Design Briefs - June 2022 - Cov1a
Medical Design Briefs - June 2022 - Cov1b
Medical Design Briefs - June 2022 - Cov1
Medical Design Briefs - June 2022 - Cov2
Medical Design Briefs - June 2022 - 1
Medical Design Briefs - June 2022 - 2
Medical Design Briefs - June 2022 - 3
Medical Design Briefs - June 2022 - 4
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Medical Design Briefs - June 2022 - 11
Medical Design Briefs - June 2022 - 12
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Medical Design Briefs - June 2022 - Cov3
Medical Design Briefs - June 2022 - Cov4a
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