Micieli et al. 419 Table 1. Model input parameters for the base-case analysis and ranges used in sensitivity analyses. Base-case value Standard error Patient characteristics Age, y 65 0.30 - 0.1 - Proportion of patients in the following health state (within 90 days of initial TIA/minor stroke) LOF allele carriers Beta Dead Carriers Non-carriers No LOF allele testing Survive without stroke/bleed Carriers Non-carriers No LOF allele testing Develop an ischemic stroke Carriers Non-carriers No LOF Allele testing Develop a fatal stroke Carriers Non-carriers No LOF allele testing Develop a severe stroke Carriers Non-carriers No LOF allele testing Develop a moderate stroke Carriers Non-carriers No LOF allele testing Develop a minor stroke Carriers Non-carriers No LOF allele testing Develop a fatal bleed Carriers 0.0028 0.0056 0.0056 0.88 0.90 0.89 0.059 0.067 0.076 0.021 0.033 0.033 0.16 0.086 0.086 0.33 0.26 0.26 0.49 0.62 0.62 0.018 0.000049 0.000099 0.000099 0.14 0.27 0.15 0.001 0.003 0.001 0.0004 0.0006 0.0006 0.0033 0.0017 0.0017 0.0087 0.0062 0.0062 0.017 0.029 0.029 0.0003 Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Beta Wang et al.11 Wang et al.8 Wang et al.11 Wang et al.11 Wang et al.8 Wang et al.11 Wang et al.11 Wang et al.8 Wang et al.11 Wang et al.11 Wang et al.8 Wang et al.11 Wang et al.11 Wang et al.8 Wang et al.11 Wang et al.11 Wang et al.8 Wang et al.11 Wang et al.11 Wang et al.8 Wang et al.11 Wang et al.11 (Continued) International Journal of Stroke, 18(4) Distribution Reference Wang et al.11 Wang et al.11