Nguyen et al. 309 Table 1. Baseline characteristics of patients in the over 24 h and 6- to 24-h groups. All (n = 166) Age, median (SD) Female sex-no. (%) NIHSS Median (IQR) Range Prior tPA (%) Type of onset: Wake-up stroke, n (%) Unwitnessed onset, n (%) Witnessed onset, n (%) Hypertension (%) Diabetes (%) AF (%) History of antithrombotic therapy (%, n = 164) ASPECTS Median (IQR) Core (IQR) mL Mismatch (IQR) mL Mismatch ratio (IQR) Hypoperfusion index (HIR) Good collaterals (%) Occlusion sites (%) ICA M1 Tandem TOAST Cardioembolic (%) Large vessel (%) Other and undetermined (%) Malignant brain edema Onset-to-arrival (IQR) (h) Door-to-perfusion imaging (IQR) (min) Perfusion imaging-to-groin (IQR) (min) Door-to-groin (IQR) (min) Groin-to-revascularization (min) Onset-to-groin (IQR) (h) 28 (16.9) 88 (53.0) 50 (30.1) 13 (7.83) 10.8 (7.89-15.1) 161 (121-244) 75.0 (53.0-109) 249 (192-348) 65.0 (55.0-90.0) 15.3 (12.1-20.5) 2 (10.0) 12 (60.0) 6 (30.0) 0 (0) 21.5 (19.0-23.7) 267 (172.0-388.0) 72.5 (56.2-83.2) 352 (231-480) 70.0 (52.5-85.0) 27.2 (25.7-30.9) 26 (17.8) 76 (52.1) 44 (30.1) 13 (8.9) 0.764 0.37 10.2 (7.48-13.8) <0.001 156 (113.0-212.0) 0.001 76.0 (53.0-109.0) 245 (188-324) 65.0 (55.0-90.0) 0.77 0.008 0.88 14.3 (11.9-18.9) <0.001 SD: standard deviation; NIHSS: National Institutes of Health Stroke Scale; IQR: interquartile range; ASPECTS: Alberta Stroke Program Early CT Score; ICA: internal carotid artery; tPA: tissue plasminogen activator; AF: atrial fibrillation; TOAST: Trial of ORG 10172 in acute stroke treatment. International Journal of Stroke, 19(3) 63.0 (56.0-69.0) 48 (28.9) 14.5 (10.0-18.0) 6-25 8 (4.82) 77 (46.4) 18 (10.8) 71 (42.8) 143 (86.1) 30 (18.1) 29 (17.5) 29 (17.7) 8.0 (8.0-9.0) 9.0 (3.0-22.0) 96.0 (62.5-138.0) 7.1 (3.68-12.9) 0.27 (0.12-0.45) 111 (66.9) 58 (34.9) 94 (56.6) 14 (8.5) Symptom onset >24 h (n = 20) 60.0 (54.0-68.0) 3 (15.0) 12.0 (10.0-18.0) 6-25 0 (0) 10 (50.0) 3 (15.0) 7 (35.0) 17 (85) 4 (20.0) 2 (10.0) 1 (5.0) 8.0 (8.0-9.5) 11.0 (0.0-24.8) 106.0 (55.8-196.0) 6.46 (3.80-14.2) 0.21 (0.08-0.39) 15 (75.0) 11 (55.0) 6 (30.0) 3 (15.0) Symptom onset 6-24 h (n = 146) 63.5 (56.2-70.0) 45 (30.8) 15.0 (11.0-18.8) 6-25 8 (6.45) 67 (45.9) 15 (10.3) 64 (43.8) 126 (86.3) 26 (17.8) 27 (18.5) 28 (19.4) 8.0 (7.0-9.0) 9.0 (0.0-20.8) 96.0 (64.0-133.0) 7.24 (3.73-12.8) 0.28 (0.13-0.46) 96 (65.8) 47 (32.2) 88 (60.3) 11 (7.53) p 0.28 0.143 0.37 0.60 0.58 >0.999 0.76 0.53 0.206 0.031 0.864 0.44 0.911 0.205 0.41 0.028