336 International Journal of Stroke 19(3) Figure 2. Association between acute and follow-up domain impairments and acute impairments predictive of follow-up impairments: (a) Associations between acute domain impairments. (b) Associations between follow-up impairments. (c) Acute impairments predicting follow-up impairments. For (a and b), tetrachoric correlation coefficient is shown with color indicating correlation coefficients. For (c), color indicates AUC; acute: x-axis, follow-up: y-axis. (a) (b) (c) Acute domain impairments predict withinand cross-domain outcomes Hierarchical regressions were conducted to identify acute factors predictive of individual domain impairments at follow-up. Each base model with only conventional predictors improved with the addition of domain-specific cognition International Journal of Stroke, 19(3) (Supplemental Figure 2). Each follow-up impairment was best predicted by the same domain impairment acutely except attention (strongest predictor was age: OR = 1.0673, p = 0.0006) and number impairment, where no predictor remained significant after correction. Full results for all domain-specific regression Supplemental Tables 4-10. models are presented in