Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P250

P250		
Otolaryngology-Head and Neck Surgery 163(1S)
Presentation schedule is subject to change. The Official Program Abstracts supplement does not reflect changes made after August 10, 2020.
reflect the pathophysiology of ASNHL. The association of
diabetes with SA may offer further insights into the basis for
this finding.
Steroid Therapy for Sudden Deafness in
Vestibular Schwannoma: A Multicenter
Study in Japan
Koichiro Wasano, MD (Presenter); Ko Hentona;
Tsubasa Kitama; Nobuyoshi Tsuzuki; Masaru Noguchi;
Yoshihiko Hiraga, MD; Naoki Oishi, MD

Otology/Neurotology

Objectives: Although it is reported that the steroid administration for sudden deafness in vestibular schwannoma (VS)
has a relatively good therapeutic effect, the reports that showed
its effect were studies on only a few tens of cases and did not
examine the second and subsequent sudden deafness.
Methods: We retrospectively examined the hospital records
in 6 tertiary care hospitals. We included the patients who were
diagnosed as sporadic VS and developed sudden hearing loss
treated by the steroid. Patients, the dose of steroid, and audiogram before and after steroid administration that were not
described in records were excluded.
Results: We examined 62 cases that developed 78 events of
sudden deafness. The therapeutic effect of the steroid was
complete recovery in 30 events, marked improvement in
4 events, partial improvement in 20 events, and no change in
24 events. The complete recovery rate was 38.5%. Among
them, the complete recovery rates of the first sudden deafness
(n = 53), the second sudden deafness (n = 17), and the third
and subsequent sudden deafness were 45.3%, 29.4%, and
12.5%, respectively. The recovery rate gradually decreased by
repeating sudden deafness.
Conclusions: We found that the recovery rate of the first sudden deafness in VS was equal to or better than the recovery
rate of sudden deafness without VS. Therefore, we consider it
important to screen VS in patients with sudden deafness, even
if the hearing loss has recovered. Furthermore, because the
second and subsequent sudden deafness becomes harder to
recover than the first sudden deafness, hearing preservation
surgery might be a choice of treatment in patients who showed
recovery from the first hearing loss.
Strong Correlation Between Serum Prestin
Level and Auditory Brainstem Response
Thresholds 24 Hours After Cochlear Injury
Khalil Keefe Rahman (Presenter); Jonas Dyhrfjeld-Johnsen;
Mathieu Petremann; James G. Naples, MD; Kourosh
Parham, MD, PhD
Objectives: We have proposed serum prestin levels as a biomarker for cochlear injury and demonstrated changes in serum
levels after cochlear injury from noise and cisplatin. To further
explore the potential of serum prestin as a biomarker, here we
explore the correlation between prestin and a functional measure of sensorineural hearing loss (SNHL), the auditory brainstem response (ABR).

Methods: Ten guinea pigs and 20 rats were used in this
study to measure baseline prestin levels and ABR thresholds.
The 10 guinea pigs were administered a single dose of intraperitoneal cisplatin (8 mg/kg) and rats were divided into
2 groups, 1 exposed to intense (120 dB SPL) whereas the
other was exposed to less intense (105-dB sound pressure
level [SPL]) noise. Hearing loss was assessed by measuring
ABR thresholds to pure tone bursts. Serum prestin levels were
quantified using enzyme-linked immunosorbent assay. ABRs
and prestin levels were measured before and 1 and 14 days
after trauma.
Results: There was no correlation between serum prestin
levels and ABR thresholds at baseline in either guinea pigs or
rats. Serum prestin levels were strongly correlated with ABR
thresholds on day 1 for cisplatin (Spearman rho = 0.78, P <
.005) and for 120-dB noise (Spearman rho = 1.0, P < .0001).
No significant correlations were found in either rats or guinea
pigs on day 14. There were also no correlations in the 105-dB
group of rats.
Conclusions: Strong correlations between its blood levels
and ABR thresholds in both noise- and cisplatin-induced
injury models further strengthen a role for serum prestin as a
biomarker for early detection of SNHL.
Subclinical Barotraumatic Ear Lesions After
Diving
Norma De Oliveira Penido, MD, PhD (Presenter);
Rafael C. Monsanto, MD; Rogério Pezato; Tiago Regis
Franco de Almeida; André Mangabeira Guimarães;
Francisco Polanski Cordeiro
Objectives: The risk of barotraumatic middle ear lesions in
patients who practice diving are well established, and the
pathophysiologic mechanisms underlying those lesions are
well known. However, data reporting middle ear lesions in
routine diving sessions (with or without symptoms of acute
injury) are lacking. Thus, the objective of this study is to quantify and analyze the presence of barotraumatic middle ear
injury in rescue teams after diving sessions.
Methods: Nineteen elite divers were consecutively evaluated during a diving rescue course (maximum depth: 6 m)
under apnea without the use of oxygen cylinders. The
patients underwent anamnesis, physical examination, and
video-otoscopy.
Results: Of  the 19 patients included in this study, 10 (52.6%)
had abnormal findings in their otoscopy (hemotympanum,
localized hematoma of the tympanic membrane, and perforation of the tympanic membrane). The most frequent clinical
symptom was aural fullness (68.4%); associated symptoms
included otalgia (26.3%), hearing loss (10.5%), and tinnitus
(10.5%). None of the patients complained of vertigo.
Conclusions: Our findings showed that the barotraumatic
lesions in routine diving sessions are more frequent than previously reported. The absence of clinical otologic symptoms
does not necessarily denote the absence of lesion of the middle ear.



Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts

Table of Contents for the Digital Edition of Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts

Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts
Contents
Accreditation Information
2020 President Duane J. Taylor, MD
2020 Annual Meeting Program Committee
2020 Star Reviewers
2020 Distinguished Service Award Recipients
2020 Honor Award Recipients
Honorary Guest Lecturers 2020
Panel Presentations
Oral Presentations
Poster Presentations
Author Index
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Intro
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Cover2
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A1
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A2
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A3
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Contents
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A5
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - A6
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Accreditation Information
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - 2020 President Duane J. Taylor, MD
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - 2020 Annual Meeting Program Committee
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P4
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - 2020 Star Reviewers
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - 2020 Honor Award Recipients
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P7
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Honorary Guest Lecturers 2020
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P9
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Panel Presentations
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P11
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P12
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Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Oral Presentations
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Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P272
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P273
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P274
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P275
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P276
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P277
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P278
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P279
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P280
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P281
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P282
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P283
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P284
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P285
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P286
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P287
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P288
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P289
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P290
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P291
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P292
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P293
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P294
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P295
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P296
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P297
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P298
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P299
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P300
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P301
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P302
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P303
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P304
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P305
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P306
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P307
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P308
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P309
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P310
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P311
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P312
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Author Index
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P316
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P317
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P318
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P319
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P320
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P321
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P322
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P323
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P324
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P325
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P326
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P327
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P328
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P329
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P330
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P331
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - P332
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Cover3
Otolaryngology - Head & Neck Surgery Supplement - 2020 Official Program Abstracts - Cover4
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